Alpha-beta T cell receptors (TCRs) are antigen specific receptors, which are essential to the immune response and are present on the cell surface of T lymphocytes. They recognize peptide-loaded major histocompatibility complexes (pMHCs) that are displayed by antigen presenting cells (APCs). Binding of alpha-beta TCR to pMHC initiates TCR-CD3 clustering on the cell surface and initiates the T cell effector functions.
FIG. 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human TCR Cbeta1 (JOVI.1) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).
Currently available formats:
Comming soon formats:
Today we introduce two mouse monoclonal antibody clones, that have been added to our portfolio: Anti-human TCR Vdelta2 (clone B6), anti-human CD200R (clone OX-108).