Trop-2 is thought to be associated with the epithelial phenotype of cancer cells and many studies have reported that epithelial markers positively correlate with its expression, whereas mesenchymal markers typically exert negative correlation.
Cytokeratins are a subfamily of intermediate filaments and are characterized by remarkable biochemical diversity. Among other applications, they also can be used as markers for detection and characterization of circulating tumor cells.
Today we introduce four mouse monoclonal antibody clones, that have been added to our portfolio: Anti-human CD49a (clone TS2/7), anti-human CD307a (clone E3), anti-human CD307c (H5), anti-human CD307d (A1).
Within the programmed cell death pathway, the interaction between PD-1 and PD-L1 and L2 particularly affects T-lymphocytes, in which they cause a phenomenon called functional exhausting, by attenuating TCR-mediated T-cell proliferation by negative costimulation control of activation of T-lymphocytes during the presentation of antigens by dendritic cells.
We present here a brief comparison of TB3, UCHT1, and MEM-57 anti-CD3 flow cytometric antibodies, that have been submitted to HLDA workshops in past.
The monoclonal antibody JOVI.1 recognizes the TRBC1+ region and enables fast and reliable assessment of clonal restriction of TCR C genes by flow cytometry.
Today we introduce two mouse monoclonal antibody clones and two rabbit polyclonal antibodies, that have been added to our portfolio: Anti-TIAR (clone 6E3), anti-human CD300b (clone B24), polyclonal anti-mCherry, and polyclonal anti-mPlum.
Today we introduce two mouse monoclonal antibody clones, that have been added to our portfolio: Anti-human TCR Vdelta2 (clone B6), anti-human CD200R (clone OX-108).
Approaching closer to the May 2022 deadline where all IVD products marketed in the EU must meet the new IVDR regulations, we are pleased to confirm to you our active steps to receive “EU Quality Management System Certificate (IVDR)” from the Notified body under the new IVDR on timely fashion.