Anti-R-RAS2 PE

Anti-R-RAS2 PE
Regulatory status
RUO
Antigen
R-RAS2
Clone
EM-50
Format
PE
Reactivity
Human
Application
Excitation laser
blue (488 nm)
Variant
0.1 mg
1P-722-C100
Ask for delivery term HERE
340.00 USD

0.025 mg
1P-722-C025
Delivery 1 week
170.00 USD
Variant
0.1 mg
11-261-C100
In stock
340.00 USD

0.1 mg
11-261-C100
In stock
170.00 USD
Product details
Description
Images
References
Isotype
Mouse IgG1 kappa
Specificity
The mouse monoclonal antibody EM-50 recognizes R-Ras2 / TC21 protein (intracellular antigen) and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras.
Application
Application details
Flow cytometry: Recommended dilution: 1-4 μg/ml. Intracellular staining.
Reactivity
Human
Immunogen
Human TC21
Concentration
0.1 mg/ml
Preparation
The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
TC21, RRAS2
Antigen description
R-Ras2 / TC21 is the only member of R-Ras family of small GTPases that shows transforming activities similar to H-Ras, N-Ras, and K-Ras, and it is also structurally similar to them. R-Ras2 seems to play an important role in activating signal transduction pathways that control cell proliferation. Its mutations are associated with the growth of certain tumors, but also overexpression of the wild type form of R-Ras2 has been frequently detected in various carcinomas. Pseudogenes of R-Ras2 gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.
Entrez Gene ID 22800
UniProt ID P62070
1P-722 FC
Separation of R-Ras2 transfected HEK-293 cells (red) from nontransfected HEK-293 cells (blue) in flow cytometry analysis (intracellular staining) stained using anti-R-RAS2 (EM-50) PE antibody (concentration in sample 1 μg/ml).

General references:

Gutierrez-Erlandsson S, Herrero-Vidal P, Fernandez-Alfara M, Hernandez-Garcia S, Gonzalo-Flores S, Mudarra-Rubio A, Fresno M, Cubelos B: R-RAS2 overexpression in tumors of the human central nervous system. Mol Cancer. 2013 Oct 23;12(1):127.
PubMed
Variant
0.1 mg
1P-722-C100
Ask for delivery term HERE
340.00 USD

0.025 mg
1P-722-C025
Delivery 1 week
170.00 USD
Variant
0.1 mg
11-261-C100
In stock
340.00 USD

0.1 mg
11-261-C100
In stock
170.00 USD

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