Anti-HLA-DQ1/DQ3 Purified

Anti-HLA-DQ1/DQ3 Purified
Regulatory status
RUO
Antigen
HLA-DQ1/DQ3
Clone
HL-37
Format
Purified
Reactivity
Pig, Human
Variant
0.1 mg
11-238-C100
In stock
143.00 USD

0.025 mg
11-238-C025
Delivery 1 week
71.50 USD
Variant
0.1 mg
11-238-C100
In stock
143.00 USD

0.025 mg
11-238-C025
Delivery 1 week
71.50 USD
Product details
Description
Images
References
SDS download
Isotype
Mouse IgG3
Specificity
The antibody HL-37 reacts with extracellular polymorphic determinant on human HLA-DQ1 and HLA-DQ3 molecules (recognized epitope was found on isolated beta chain of DQ1), but does not react with HLA-DQ2. DQ is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).
Application details
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Western blotting: non-reducing conditions.
Reactivity
Pig, Human
Immunogen
Burkitt's lymphoma cell line Raji.
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Antigen description
The antibody HL-37 reacts with polymorphic determinant on human HLA-DQ1 and HLA-DQ3 molecules (recognized epitope was found on isolated beta chain of DQ1), but does not react with HLA-DQ2. DQ is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).
11-238 FC
Flow cytometry analysis (surface staining) of human peripheral blood cells with anti-HLA-DQ1+DQ3 (HL-37) purified, GAM-APC.

Product specific references:

Horejsi V, Nemec M, Angelisova P, Kristofova H, Gorga JC, Hilgert I: Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens. Tissue Antigens. 1986 Nov;28(5):288-97.
PubMed
Variant
0.1 mg
11-238-C100
In stock
143.00 USD

0.025 mg
11-238-C025
Delivery 1 week
71.50 USD
Variant
0.1 mg
11-238-C100
In stock
143.00 USD

0.025 mg
11-238-C025
Delivery 1 week
71.50 USD

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