Anti-Hu CD187 PE

Anti-Hu CD187 PE
Regulatory status
RUO
Antigen
CD187
Clone
10D1-J16
Format
PE
Reactivity
Human
Application
Excitation laser
blue (488 nm)
Variant
100 tests
1P-879-T100
In stock
220.00 USD
Variant
0.1 mg
11-261-C100
In stock
220.00 USD
Product details
Description
Images
References
Isotype
Mouse IgG2a kappa
Specificity
The mouse monoclonal antibody 10D1-J16 recognizes an extracellular epitope on CD187/CXCR7, a transmembrane protein of chemokine receptor family.
Application
Application details
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity
Human
Preparation
The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
CXCR7, RDC1, GPR159, ACKR3
Antigen description
CD187 (CXCR7) is a member of chemokine receptor family, but with discussed specificity. It is expressed in various tissues and cells, such as placenta, urinary bladder, fetal liver cells, tumor cells, activated endothelium, monocytes, lymphocytes, mature dendritic cells, and other.
Entrez Gene ID 57007
UniProt ID P25106
1P-879_FC_Histogram
Separation of MCF-7 cells stained using anti-human CD187 (10D1-J16) PE antibody (10 μl reagent per million cells in 100 μl of cell suspension, red-filled) from MCF-7 cells stained using mouse IgG2a isotype control (MOPC-173) PE antibody (concentration in sample 5 μg/ml, same as CD187 PE concentration, black-dashed) in flow cytometry analysis (surface staining) of MCF-7 cell suspension.

Product specific references:

Doijen J, Van Loy T, De Haes W, Landuyt B, Luyten W, Schoofs L, Schols D: Signaling properties of the human chemokine receptors CXCR4 and CXCR7 by cellular electric impedance measurements. PLoS One. 2017 Sep 25;12(9):e0185354.
PubMed
Espinoza-Sánchez NA, Vadillo E, Balandrán JC, Monroy-García A, Pelayo R, Fuentes-Pananá EM: Evidence of lateral transmission of aggressive features between different types of breast cancer cells. Int J Oncol. 2017 Nov;51(5):1482-1496.
PubMed
Guan L, Li X, Wei J, Liang Z, Yang J, Weng X, Wu X: Antigen-specific CD8+ memory stem T cells generated from human peripheral blood effectively eradicate allogeneic targets in mice. Stem Cell Res Ther. 2018 Dec 7;9(1):337.
PubMed
Variant
100 tests
1P-879-T100
In stock
220.00 USD
Variant
0.1 mg
11-261-C100
In stock
220.00 USD

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