Exbio — Research products — Antibodies — Microbiology and virology — Anti-HSV-1/HSV-2 glycoprotein B Alexa Fluor<sup>®</sup> 488

Anti-HSV-1/HSV-2 glycoprotein B Alexa Fluor^® 488

Regulatory status

RUO

Antigen

HSV-1/HSV-2 glycoprotein B

Clone

T111

Format

Alexa Fluor^® 488

Reactivity

Herpes Simplex Virus

Application

ICC (QC tested)

Excitation laser

blue (488 nm)

Variant

0.1 mg

A4-330-C100

In stock

248.60 USD

Variant

0.1 mg

A4-330-C100

In stock

248.60 USD

Contact distributor

Product details

Description

References

SDS download

Isotype

Mouse IgG2b

Specificity

The antibody T111 recognizes gB antigen of both HSV1 and HSV2 (Herpes Simplex Virus type 1 and 2), a dsDNA virus, member of Herpesviridae family.

Application

ICC (QC tested)

Application details

Immunocytochemistry: Recommended dilution 2-10 μg/ml.

Reactivity

Herpes Simplex Virus

Immunogen

Exctract of HSV-1 infected VERO (green monkey kidney) cells.

Concentration

0.1 mg/ml

Preparation

Purified antibody is conjugated with Alexa Fluor^® 488 NHS ester under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Formulation

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Alexa Fluor^®, Pacific Blue™ and Pacific Orange™ are registered trademarks of Life Technologies Corporation.

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com.

Other names

HSVGB, HSV-1 gB, HSV-2 gB

Antigen description

Herpes simplex virus (HSV) is a virus that manifests itself in two common viral infections. There are actually two types of herpes simplex virus, HSV1 and HSV2. These are very similar in many ways, and both can cause either oral herpes or genital herpes. HSV1 - most commonly develops into oral herpes infecting the lips (fever blisters or cold sores). HSV1 can also infect the genital area causing sores to develop. HSV2 - generally infects the genital area (genital herpes); however, HSV2 can also infect the mouth.

Entrez Gene ID 24271469

UniProt ID P10211

Product specific references:

Bystricka M, Zatovicova M, Petrikova M, Solarikova L, Russ G, Ziegler T: Monoclonal antibodies suitable for type-specific identification of herpes simplex viruses by a rapid culture assay. Acta Virol. 1999 Dec;43(6):399-402.
PubMed

Bystricka M, Petrikova M, Zatovicova M, Solarikova L, Kostolansky F, Mucha V, Russ G: Monoclonal antibodies to the distinct antigenic sites on glycoproteins C and B and their protective abilities in herpes simplex virus infection. Acta Virol. 1997 Feb;41(1):5-12.
PubMed

Bystricka M, Vancikova M, Kasalova M, Rajcani J, Kostal M, Muranyiova M, Polakova K, Russ G: Type-common and type-specific monoclonal antibodies to herpes simplex virus types 1 and 2. Acta Virol. 1991 Apr;35(2):152-64.
PubMed