Exbio — Research products — Antibodies — Microbiology and virology — Anti-GlcB (M. tuberculosis) Purified

Anti-GlcB (M. tuberculosis) Purified

Regulatory status

RUO

Antigen

GlcB (M. tuberculosis)

Clone

PAb (192)

Format

Purified

Reactivity

Mycobacterium tuberculosis

Application

ELISA, WB

Variant

0.1 mg

11-192-C100

In stock

198.00 USD

Variant

0.1 mg

11-192-C100

In stock

198.00 USD

Contact distributor

Product details

Description

Images

References

SDS download

Isotype

Rabbit polyclonal

Specificity

The rabbit polyclonal antibody to GlcB reacts with Mycobacterium tuberculosis protein GlcB (malate synthase, Rv1837c).

Application

ELISA, WB

Reactivity

Mycobacterium tuberculosis

Immunogen

Recombinant GlcB protein (produced in E. coli)

Concentration

1 mg/ml

Preparation

Purified by ligand affinity chromatography.

Formulation

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Other names

Rv1837c

Antigen description

The Mycobacterium tuberculosis antigen GlcB (malate synthase) catalyzes synthesis of malate from glyoxylate and acetyl-CoA. This reaction is part of the glyoxylate cycle, which allows the bacterium to derive its carbon requirements from two-carbon compounds by bypassing the two carbocylation steps of the cytric acid cycle. This enzyme is up-regulated in response to phagocytosis and it is a virulence or persistence factor.

Entrez Gene ID 885713

UniProt ID P9WK17

Western blotting analysis of polyclonal anti-Mycobacterium tuberculosis antigen GlcB. A) cell lysate of non-transfected E. coli B) cell lysate of GlcB-transfected E. coli