Anti-CFP-10 (M. tuberculosis) Purified

Anti-CFP-10 (M. tuberculosis) Purified
Regulatory status
RUO
Antigen
CFP-10 (M. tuberculosis)
Clone
PAb (490)
Format
Purified
Reactivity
Mycobacterium tuberculosis
Application
Variant
0.1 mg
11-490-C100
In stock
198.00 USD

0.025 mg
11-490-C025
Delivery 1 week
99.00 USD
Variant
0.1 mg
11-490-C100
In stock
198.00 USD

0.025 mg
11-490-C025
Delivery 1 week
99.00 USD
Product details
Description
References
SDS download
Isotype
Rabbit polyclonal
Specificity
The rabbit polyclonal antibody to CFP10 recognizes the CFP10 (Rv3874) protein of Mycobacterium tuberculosis and Mycobacterium bovis.
Application
Application details
Western blotting: Recommended dilution 0.5-1 μg/ml, reducing conditions.
Reactivity
Mycobacterium tuberculosis
Immunogen
CFP10 (Rv3874) of Mycobacterium tuberculosis
Concentration
1 mg/ml
Preparation
Purified by ligand affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
CFP-10, CFP10, Rv3874, LHP, Mycobacterium tuberculosis esxB antigen
Antigen description
The Mycobacterium tuberculosis antigen CFP-10 (10 kDa culture filtrate antigen EsxB; LHP), also known as Rv3874, plays important role in mycobacterial virulence. It forms a complex with EsaT-6 protein.
Entrez Gene ID 886194
UniProt ID P9WNK5

General references:

Yang H, Chen H, Liu Z, Ma H, Qin L, Jin R, Zheng R, Feng Y, Cui Z, Wang J, Liu J, Hu Z: A novel B-cell epitope identified within Mycobacterium tuberculosis CFP10/ESAT-6 protein. PLoS One. 2013;8(1):e52848.
PubMed
Arlehamn CS, Sidney J, Henderson R, Greenbaum JA, James EA, Moutaftsi M, Coler R, McKinney DM, Park D, Taplitz R, Kwok WW, Grey H, Peters B, Sette A: Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ). J Immunol. 2012 May 15;188(10):5020-31.
PubMed
Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE, Tekaia F, Badcock K, Basham D, Brown D, Chillingworth T, Connor R, Davies R, Devlin K, Feltwell T, Gentles S, Hamlin N, Holroyd S, Hornsby T, Jagels K, Krogh A, McLean J, Moule S, Murphy L, Oliver K, Osborne J, Quail MA, Rajandream MA, Rogers J, Rutter S, Seeger K, Skelton J, Squares R, Squares S, Sulston JE, Taylor K, Whitehead S, Barrell BG: Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature. 1998 Jun 11;393(6685):537-44. Erratum in: Nature 1998 Nov 12;396(6707):190.
PubMed
Variant
0.1 mg
11-490-C100
In stock
198.00 USD

0.025 mg
11-490-C025
Delivery 1 week
99.00 USD
Variant
0.1 mg
11-490-C100
In stock
198.00 USD

0.025 mg
11-490-C025
Delivery 1 week
99.00 USD