Exbio — Research products — Antibodies — Microbiology and virology — Anti-CFP-10 (M. tuberculosis) Purified

Anti-CFP-10 (M. tuberculosis) Purified

Regulatory status

RUO

Antigen

CFP-10 (M. tuberculosis)

Clone

PAb (490)

Format

Purified

Reactivity

Mycobacterium tuberculosis

Application

Variant

0.1 mg

11-490-C100

In stock

198.00 USD

0.025 mg

11-490-C025

Delivery 1 week

99.00 USD

Variant

0.1 mg

11-490-C100

In stock

198.00 USD

0.025 mg

11-490-C025

Delivery 1 week

99.00 USD

Contact distributor

Product details

Description

References

SDS download

Isotype

Rabbit polyclonal

Specificity

The rabbit polyclonal antibody to CFP10 recognizes the CFP10 (Rv3874) protein of Mycobacterium tuberculosis and Mycobacterium bovis.

Application

Application details

Western blotting: Recommended dilution 0.5-1 μg/ml, reducing conditions.

Reactivity

Mycobacterium tuberculosis

Immunogen

CFP10 (Rv3874) of Mycobacterium tuberculosis

Concentration

1 mg/ml

Preparation

Purified by ligand affinity chromatography.

Formulation

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Other names

CFP-10, CFP10, Rv3874, LHP, Mycobacterium tuberculosis esxB antigen

Antigen description

The Mycobacterium tuberculosis antigen CFP-10 (10 kDa culture filtrate antigen EsxB; LHP), also known as Rv3874, plays important role in mycobacterial virulence. It forms a complex with EsaT-6 protein.

Entrez Gene ID 886194

UniProt ID P9WNK5

General references:

Yang H, Chen H, Liu Z, Ma H, Qin L, Jin R, Zheng R, Feng Y, Cui Z, Wang J, Liu J, Hu Z: A novel B-cell epitope identified within Mycobacterium tuberculosis CFP10/ESAT-6 protein. PLoS One. 2013;8(1):e52848.
PubMed

Arlehamn CS, Sidney J, Henderson R, Greenbaum JA, James EA, Moutaftsi M, Coler R, McKinney DM, Park D, Taplitz R, Kwok WW, Grey H, Peters B, Sette A: Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ). J Immunol. 2012 May 15;188(10):5020-31.
PubMed

Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE, Tekaia F, Badcock K, Basham D, Brown D, Chillingworth T, Connor R, Davies R, Devlin K, Feltwell T, Gentles S, Hamlin N, Holroyd S, Hornsby T, Jagels K, Krogh A, McLean J, Moule S, Murphy L, Oliver K, Osborne J, Quail MA, Rajandream MA, Rogers J, Rutter S, Seeger K, Skelton J, Squares R, Squares S, Sulston JE, Taylor K, Whitehead S, Barrell BG: Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature. 1998 Jun 11;393(6685):537-44. Erratum in: Nature 1998 Nov 12;396(6707):190.
PubMed