Exbio — Research products — Antibodies — Microbiology and virology — Anti-Ag85b (M. tuberculosis) Purified

Anti-Ag85b (M. tuberculosis) Purified

Regulatory status

RUO

Antigen

Ag85b (M. tuberculosis)

Clone

PAb (189)

Format

Purified

Reactivity

Mycobacterium tuberculosis

Application

ELISA, WB

Variant

0.1 mg

11-189-C100

In stock

198.00 USD

Variant

0.1 mg

11-189-C100

In stock

198.00 USD

Contact distributor

Product details

Description

References

SDS download

Isotype

Rabbit polyclonal

Specificity

The rabbit polyclonal antibody to Ag85b reacts with the Mycobacterium tuberculosis protein Ag85b (FbpB), which is a diacylglycerol acyltransferase/mycolyltransferase.

Application

ELISA, WB

Reactivity

Mycobacterium tuberculosis

Immunogen

Recombinant Mycobacterium tuberculosis Ag85b produced in E. coli

Concentration

1 mg/ml

Preparation

Purified by ligand affinity chromatography.

Formulation

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Other names

FbpB, mycolyl transferase 85B

Antigen description

The Mycobacterium tuberculosis antigen Ag85b, also known as FbpB secreted antigen, 85-B FbpB (85B), antigen 85 complex B, mycolyl transferase 85B, fibronectin-binding protein B, or extracellular alpha-antigen, facilitates Mycobacterium attachment to host cells via fibronectin. It is also involved in maintaining cell wall integrity through the transfer of mycolyic acids (diacylglycerol acyltransferase/mycolyltransferase activity).

Entrez Gene ID 885785

UniProt ID I6YBV4

General references:

Backus KM, Dolan MA, Barry CS, Joe M, McPhie P, Boshoff HI, Lowary TL, Davis BG, Barry CE: The three Mycobacterium tuberculosis antigen 85 isoforms have unique substrates and activities determined by non-active site regions. J Biol Chem. 2014 Sep 5;289(36):25041-53.
PubMed