Anti-Ag85b (M. tuberculosis) Purified

Anti-Ag85b (M. tuberculosis) Purified
Regulatory status
RUO
Antigen
Ag85b (M. tuberculosis)
Clone
PAb (189)
Format
Purified
Reactivity
Mycobacterium tuberculosis
Application
Variant
0.1 mg
11-189-C100
In stock
198.00 USD
Variant
0.1 mg
11-189-C100
In stock
198.00 USD
Product details
Description
References
SDS download
Isotype
Rabbit polyclonal
Specificity
The rabbit polyclonal antibody to Ag85b reacts with the Mycobacterium tuberculosis protein Ag85b (FbpB), which is a diacylglycerol acyltransferase/mycolyltransferase.
Application
Reactivity
Mycobacterium tuberculosis
Immunogen
Recombinant Mycobacterium tuberculosis Ag85b produced in E. coli
Concentration
1 mg/ml
Preparation
Purified by ligand affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
FbpB, mycolyl transferase 85B
Antigen description
The Mycobacterium tuberculosis antigen Ag85b, also known as FbpB secreted antigen, 85-B FbpB (85B), antigen 85 complex B, mycolyl transferase 85B, fibronectin-binding protein B, or extracellular alpha-antigen, facilitates Mycobacterium attachment to host cells via fibronectin. It is also involved in maintaining cell wall integrity through the transfer of mycolyic acids (diacylglycerol acyltransferase/mycolyltransferase activity).
Entrez Gene ID 885785
UniProt ID I6YBV4

General references:

Backus KM, Dolan MA, Barry CS, Joe M, McPhie P, Boshoff HI, Lowary TL, Davis BG, Barry CE: The three Mycobacterium tuberculosis antigen 85 isoforms have unique substrates and activities determined by non-active site regions. J Biol Chem. 2014 Sep 5;289(36):25041-53.
PubMed
Variant
0.1 mg
11-189-C100
In stock
198.00 USD
Variant
0.1 mg
11-189-C100
In stock
198.00 USD