Anti-Acr2 (M. tuberculosis) Purified

Anti-Acr2 (M. tuberculosis) Purified
Regulatory status
RUO
Antigen
Acr2 (M. tuberculosis)
Clone
PAb (188)
Format
Purified
Reactivity
Mycobacterium tuberculosis
Application
Variant
0.1 mg
11-188-C100
In stock
198.00 USD
Variant
0.1 mg
11-188-C100
In stock
198.00 USD
Product details
Description
Images
References
SDS download
Isotype
Rabbit polyclonal
Specificity
The rabbit polyclonal antibody to Acr2 reacts with Mycobacterium tuberculosis protein Acr2 (Rv0251c, Hsp20).
Application
Reactivity
Mycobacterium tuberculosis
Immunogen
Recombinant Acr2 protein (produced in E. coli)
Concentration
1 mg/ml
Preparation
Purified by ligand affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
Hsp20, HrpA
Antigen description
The Mycobacterium tuberculosis antigen Acr2 (alpha-crystallin-related protein 2), also known as HrpA or Hsp20, is a small heat shock protein, which forms oligomeric assemblies. Expression of Acr2 is induced by heat shock, oxidative stress, and uptake by macrophages. It evokes a vigorous early immune response.
11-188 WB
Western blotting analysis of polyclonal anti-Mycobacterium tuberculosis antigen Acr2. A) cell lysate of non-transfected E. coli B) cell lysate of Acr2-transfected E. coli

General references:

Stewart GR, Newton SM, Wilkinson KA, Humphreys IR, Murphy HN, Robertson BD, Wilkinson RJ, Young DB: The stress-responsive chaperone alpha-crystallin 2 is required for pathogenesis of Mycobacterium tuberculosis. Mol Microbiol. 2005 Feb;55(4):1127-37.
PubMed
Wilkinson KA, Stewart GR, Newton SM, Vordermeier HM, Wain JR, Murphy HN, Horner K, Young DB, Wilkinson RJ: Infection biology of a novel alpha-crystallin of Mycobacterium tuberculosis: Acr2. J Immunol. 2005 Apr 1;174(7):4237-43.
PubMed
Kennaway CK, Benesch JL, Gohlke U, Wang L, Robinson CV, Orlova EV, Saibil HR, Keep NH: Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis. J Biol Chem. 2005 Sep 30;280(39):33419-25.
PubMed
Variant
0.1 mg
11-188-C100
In stock
198.00 USD
Variant
0.1 mg
11-188-C100
In stock
198.00 USD