Exbio — Research products — Antibodies — Small organic molecules — Anti-Benzo[a]pyrene Purified

Anti-Benzo[a]pyrene Purified

Regulatory status

RUO

Antigen

Benzo[a]pyrene

Clone

BAP-13

Format

Purified

Application

ELISA, ICC

Variant

0.1 mg

11-339-C100

In stock

165.00 USD

0.025 mg

11-339-C025

Delivery 1 week

82.50 USD

Variant

0.1 mg

11-339-C100

In stock

165.00 USD

0.025 mg

11-339-C025

Delivery 1 week

82.50 USD

Contact distributor

Product details

Images

References

SDS download

Isotype

Mouse IgG1

Specificity

The antibody BAP-13 is specific for Polynuclear Aromatic Hydrocarbon and inhibits DNA adduct formation (this ability was investigated in rat liver microsomes spiked with calf thymus DNA and 7,8-diol-B[a]P).

Application

ELISA, ICC

Application details

Immunocytochemistry: The antibody BAP-13 is suitable for immunocytochemical analysis of DNA and protein adducts of benzo[a]pyrene in tissues of various species.

Immunogen

Benzo[a]pyrenyl-1-butyric acid conjugated to BSA.

Concentration

1 mg/ml

Preparation

Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Formulation

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

ELISA detection of benzo(a)pyrene using mouse monoclonal antibody BAP-13, compared with isotype control antibody PPV-06.

Product specific references:

Suchanek M, Scharnweber T, Fisher M, Knopp D, Niessner R: Monoclonal antibodies specific to polynuclear aromatic hydrocarbons. Folia Biol (Praha). 2001;47(3):106-7.

Scharnweber T, Fisher M, Suchanek M, Knopp D, Niessner R: Monoclonal antibody to polycyclic aromatic hydrocarbons based on a new benzo[a]pyrene immunogen. Fresenius J Anal Chem. 2001 Nov;371(5):578-85.
PubMed

De Buck SS, Bouche FB, Brandenburger A, Muller CP: Modulation of the metabolism and adverse effects of benzo[a]pyrene by a specific antibody: a novel host factor in environmental carcinogenesis? Carcinogenesis. 2005 Apr;26(4):835-44.
PubMed