Anti-Lysozyme Purified

Anti-Lysozyme Purified
Regulatory status
RUO
Antigen
Lysozyme
Clone
LZ598-10G9
Format
Purified
Reactivity
Human
Variant
0.1 mg
11-800-C100
In stock
130.00 USD

0.025 mg
11-800-C025
In stock
65.00 USD
Variant
0.1 mg
11-261-C100
In stock
130.00 USD

0.1 mg
11-261-C100
In stock
65.00 USD
Product details
Description
Images
References
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody LZ598-10G9 recognizes lysozyme, an approximately 17 kDa antibacterial enzyme, which is being used as a marker for the lineage diagnosis of acute leukemias (intracellular antigen).
Application details
Flow cytometry: Intracellular staining; recommended dilution: 1-12 µg/ml. Excellent.
Immunohistochemistry (paraffin sections): Positive tissue: tonsil.
Reactivity
Human
Immunogen
human lysozyme
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
LZM, LYZF1
Antigen description
Lysozyme is anti-bacterial enzyme found mainly in milk, saliva, tears, plasma, spleen, mucus, and leukocytes (e.g. in cytoplasmic granules of neutrophils). It damages bacterial cell walls by hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. Lysozyme is part of the innate immune system. It protects wet body surfaces, such as conjunctiva. Reduced lysozyme levels have been associated with bronchopulmonary dysplasia in newborns. On the other hand high lysozyme blood levels produced for example by myelomonocytic leukemia cells can lead to kidney failure and low blood potassium.
Entrez Gene ID 4069
UniProt ID P61626
11-800 FC
Flow cytometry analysis (intracellular staining) of lysozyme in human peripheral blood with anti-lysozyme (LZ598-10G9) purified, GAM-FITC.
11-800_ICC
Immunocytochemistry staining of lysozyme (green; A, C) in Hep G2 cells (A, B, C) using mouse monoclonal antibody LZ598-10G9. Actin decorated with phalloidin (red), DNA stained with DAPI (blue). Figure D represents SK-BR-3 cells with no expression of lysozyme, stained with LZ598-10G9 antibody (no background signal).
11-800 MC
Mass cytometry (intracellular staining) of PBMC after Ficoll-Paque separation with anti-human lysozyme (LZ598-10G9) Gd155. Gated on native.

General references:

Strobl H, Knapp W: Myeloid cell-associated lysosomal proteins as flow cytometry markers for leukocyte lineage classification. J Biol Regul Homeost Agents. 2004 Jul-Dec;18(3-4):335-9.
PubMed
Variant
0.1 mg
11-800-C100
In stock
130.00 USD

0.025 mg
11-800-C025
In stock
65.00 USD
Variant
0.1 mg
11-261-C100
In stock
130.00 USD

0.1 mg
11-261-C100
In stock
65.00 USD

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