Anti-Lysozyme FITC

Anti-Lysozyme FITC
Regulatory status
RUO
Antigen
Lysozyme
Clone
LZ598-10G9
Format
FITC
Reactivity
Human
Application
Excitation laser
blue (488 nm)
Variant
0.1 mg
1F-800-C100
In stock
198.00 USD

0.025 mg
1F-800-C025
Delivery 1 week
99.00 USD
Variant
0.1 mg
1F-800-C100
In stock
198.00 USD

0.025 mg
1F-800-C025
Delivery 1 week
99.00 USD
Product details
Description
Images
References
SDS download
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody LZ598-10G9 recognizes lysozyme, an approximately 17 kDa antibacterial enzyme, which is being used as a marker for the lineage diagnosis of acute leukemias (intracellular antigen).
Application
Application details
Flow cytometry: Recommended dilution: 1-3 μg/ml. Intracellular staining.
Reactivity
Human
Immunogen
human lysozyme
Concentration
1 mg/ml
Preparation
Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
LZM, LYZF1
Antigen description
Lysozyme is anti-bacterial enzyme found mainly in milk, saliva, tears, plasma, spleen, mucus, and leukocytes (e.g. in cytoplasmic granules of neutrophils). It damages bacterial cell walls by hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. Lysozyme is part of the innate immune system. It protects wet body surfaces, such as conjunctiva. Reduced lysozyme levels have been associated with bronchopulmonary dysplasia in newborns. On the other hand high lysozyme blood levels produced for example by myelomonocytic leukemia cells can lead to kidney failure and low blood potassium.
Entrez Gene ID 4069
UniProt ID P61626
1F-800 FC
Flow cytometry analysis (intracellular staining) of lysozyme in human peripheral blood with anti-lysozyme (LZ598-10G9) FITC.

General references:

Strobl H, Knapp W: Myeloid cell-associated lysosomal proteins as flow cytometry markers for leukocyte lineage classification. J Biol Regul Homeost Agents. 2004 Jul-Dec;18(3-4):335-9.
PubMed
Variant
0.1 mg
1F-800-C100
In stock
198.00 USD

0.025 mg
1F-800-C025
Delivery 1 week
99.00 USD
Variant
0.1 mg
1F-800-C100
In stock
198.00 USD

0.025 mg
1F-800-C025
Delivery 1 week
99.00 USD

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