Anti-Lactoferrin Purified

Anti-Lactoferrin Purified
Regulatory status
RUO
Antigen
Lactoferrin
Clone
LF5-1D2
Format
Purified
Reactivity
Human
Variant
0.1 mg
11-128-C100
In stock
130.00 USD

0.025 mg
11-128-C025
Delivery 1 week
65.00 USD
Variant
0.1 mg
11-261-C100
In stock
130.00 USD

0.1 mg
11-261-C100
In stock
65.00 USD
Product details
Description
Images
References
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody LF5-1D2 recognizes lactoferrin, an iron-binding secreted glycoprotein of about 90 kDa, which has anti-inflammatory, immunomodulatory and anti-microbial properties.
Application details
Flow cytometry: Recommended dilution: 1-4 µg/ml. Intracellular staining.
Reactivity
Human
Immunogen
human lactoferrin
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
LF, Lactotransferrin, LTF
Antigen description
Lactoferrin is an iron-binding glycoprotein of the transferrin family, which is released to most biological fluids, with particularly high levels in milk. It has anti-inflammatory (e.g. sequestering of lipopolysaccharides), anti-microbial (e.g. blocking of viral attachment to the target cell), and immunomodulatory properties and can prevent infections in young children. Lactoferrin is considered to bridge the innate and adaptive immune responses. It also participates in iron homeostasis, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Besides biological fluids it is also found in the secondary granules of neutrophils.
Entrez Gene ID 4057
UniProt ID P02788
11-128 FC
Flow cytometry analysis (intracellular staining) of human peripheral blood cells using anti-lactoferrin (LF5-1D2) purified, GAM-APC.

General references:

Turin CG, Zea-Vera A, Pezo A, Cruz K, Zegarra J, Bellomo S, Cam L, Llanos R, Castañeda A, Tucto L, Ochoa TJ; NEOLACTO Research Group: Lactoferrin for prevention of neonatal sepsis. Biometals. 2014 Oct;27(5):1007-16. doi: 10.1007/s10534-014-9754-3.
PubMed
Siqueiros-Cendón T, Arévalo-Gallegos S, Iglesias-Figueroa BF, García-Montoya IA, Salazar-Martínez J, Rascón-Cruz Q: Immunomodulatory effects of lactoferrin. Acta Pharmacol Sin. 2014 May;35(5):557-66.
PubMed

Product specific references:

Zwirzitz A, Reiter M, Skrabana R, Ohradanova-Repic A, Majdic O, Gutekova M, Cehlar O, Petrovčíková E, Kutejova E, Stanek G, Stockinger H, Leksa V: Lactoferrin is a natural inhibitor of plasminogen activation. J Biol Chem 2018; 293(22) 8600-8613
PubMed
Variant
0.1 mg
11-128-C100
In stock
130.00 USD

0.025 mg
11-128-C025
Delivery 1 week
65.00 USD
Variant
0.1 mg
11-261-C100
In stock
130.00 USD

0.1 mg
11-261-C100
In stock
65.00 USD

Related products

-134%
Reg. statusRUO
ApplicationFC
100 tests
200.00 USD
-134%
CloneMOPC-21
Reg. statusRUO
0.1 mg
105.00 USD