Exbio — Research products — Antibodies — Serum, plasma, and secreted proteins — Anti-Hu IgA Purified

Anti-Hu IgA Purified

Anti-Hu IgA Purified
Regulatory status
RUO
Antigen
IgA
Clone
AD3
Format
Purified
Reactivity
Human
Application
ELISA, IHC(P)
Variant
0.1 mg
11-322-C100
Ask for delivery term HERE
100.00 USD
0.025 mg
11-322-C025
In stock
50.00 USD
Variant
0.1 mg
11-322-C100
Ask for delivery term HERE
100.00 USD
0.025 mg
11-322-C025
In stock
50.00 USD
Contact distributor
Product details
Description
Images
References
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody AD3 reacts with alpha-chain of human IgA1 and IgA2.
Application
ELISA, IHC(P)
Application details
Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/ml; positive tissue: colon.
Reactivity
Human
Immunogen
Purified human IgA.
Concentration
1 mg/ml
Preparation
Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
Immunoglobulin A
Antigen description
Immunoglobulin A (IgA) is the major immunoglobulin class in body secretions that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract. Its serum concentration is approximately 0.2 g/l and biological survival (T1/2 in plasma) 6 days. Plasma IgA is predominantly monomeric (160 kDa) and of the IgA1 subclass, and is mostly produced in the bone marrow. Over half of IgA produced by the intestinal lamina propria plasmocytes is in oligomeric form and 35% of it is IgA2.
11-322_IHC
Immunohistochemistry staining of human colon (paraffin sections) with anti-IgA (clone AD3). Commercially tested by LifeSpan BioSciences.

General references:

Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95.
PubMed
Fuller JM, Keyser JW: Serum immunoglobulins after surgical operation. Clin Chem. 1975 May;21(6):667-71.
PubMed
Balogh Z, Merétey K, Falus A, Bozsóky S: Serological abnormalities in juvenile chronic arthritis: a review of 46 cases. Ann Rheum Dis. 1980 Apr;39(2):129-34.
PubMed
Jonard PP, Rambaud JC, Dive C, Vaerman JP, Galian A, Delacroix DL: Secretion of immunoglobulins and plasma proteins from the jejunal mucosa. Transport rate and origin of polymeric immunoglobulin A. J Clin Invest. 1984 Aug;74(2):525-35.
PubMed

Product specific references:

Galkin OY, Gorshunov YV, Besarab OB, Ivanova OM: Development and characterization of highly informative ELISA for the detection of IgG and IgA antibodies to Сhlamydia trachomatis. Ukr. Biochem. J., 2018, Vol. 90, N 3, 70-83
PubMed
Senant M, Bordereau P, Tartour E, Dragon-Durey MA: Analytical validation of an alternative method to quantify specific antibodies in 3 applications. J Immunol Methods. 2019 Jan;464:40-46.
PubMed
Variant
0.1 mg
11-322-C100
Ask for delivery term HERE
100.00 USD
0.025 mg
11-322-C025
In stock
50.00 USD
Variant
0.1 mg
11-322-C100
Ask for delivery term HERE
100.00 USD
0.025 mg
11-322-C025
In stock
50.00 USD
Contact distributor
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