Exbio — Research products — Antibodies — Serum, plasma, and secreted proteins — Anti-Hu IgA Purified

Anti-Hu IgA Purified

Regulatory status

RUO

Antigen

IgA

Clone

AD2.947

Format

Purified

Reactivity

Human

Application

ELISA, IHC(P)

Variant

0.1 mg

11-947-C100

In stock

154.00 USD

Variant

0.1 mg

11-947-C100

In stock

154.00 USD

Contact distributor

Product details

Description

Images

References

SDS download

Isotype

Mouse IgG1

Specificity

The mouse monoclonal antibody AD2.947 reacts with human IgA1 and IgA2.

Application

ELISA, IHC(P)

Reactivity

Human

Immunogen

human IgA

Concentration

1 mg/ml

Preparation

Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Formulation

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Other names

Immunoglobulin A

Antigen description

Immunoglobulin A (IgA) is the major immunoglobulin class in body secretions that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract. Its serum concentration is approximately 0.2 g/l and biological survival (T1/2 in plasma) 6 days. Plasma IgA is predominantly monomeric (160 kDa) and of the IgA1 subclass, and is mostly produced in the bone marrow. Over half of IgA produced by the intestinal lamina propria plasmocytes is in oligomeric form and 35% of it is IgA2.

ELISA analysis of IgA in 1000x diluted human plasma using mouse monoclonal antibodies AD2.947 and AD3 (0.016 - 10 μg/ml).

General references:

Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95.
PubMed

Fuller JM, Keyser JW: Serum immunoglobulins after surgical operation. Clin Chem. 1975 May;21(6):667-71.
PubMed

Balogh Z, Merétey K, Falus A, Bozsóky S: Serological abnormalities in juvenile chronic arthritis: a review of 46 cases. Ann Rheum Dis. 1980 Apr;39(2):129-34.
PubMed

Jonard PP, Rambaud JC, Dive C, Vaerman JP, Galian A, Delacroix DL: Secretion of immunoglobulins and plasma proteins from the jejunal mucosa. Transport rate and origin of polymeric immunoglobulin A. J Clin Invest. 1984 Aug;74(2):525-35.
PubMed