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Exbio
—
Research products
—
Antibodies
—
Serum, plasma, and secreted proteins
—
Anti-Hu IgA Purified
Anti-Hu IgA Purified
Regulatory status
RUO
Antigen
IgA
Clone
AD2.947
Format
Purified
Reactivity
Human
Application
ELISA, IHC(P)
Variant
0.1 mg
11-947-C100
In stock
140.00 USD
Variant
0.1 mg
11-947-C100
In stock
140.00 USD
Contact distributor
Product details
Description
Images
References
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody AD2.947 reacts with human IgA1 and IgA2.
Application
ELISA, IHC(P)
Reactivity
Human
Immunogen
human IgA
Concentration
1 mg/ml
Preparation
Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
Immunoglobulin A
Antigen description
Immunoglobulin A (IgA) is the major immunoglobulin class in body secretions that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract. Its serum concentration is approximately 0.2 g/l and biological survival (T1/2 in plasma) 6 days. Plasma IgA is predominantly monomeric (160 kDa) and of the IgA1 subclass, and is mostly produced in the bone marrow. Over half of IgA produced by the intestinal lamina propria plasmocytes is in oligomeric form and 35% of it is IgA2.
ELISA analysis of IgA in 1000x diluted human plasma using mouse monoclonal antibodies AD2.947 and AD3 (0.016 - 10 μg/ml).
General references:
Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95.
PubMed
Fuller JM, Keyser JW: Serum immunoglobulins after surgical operation. Clin Chem. 1975 May;21(6):667-71.
PubMed
Balogh Z, Merétey K, Falus A, Bozsóky S: Serological abnormalities in juvenile chronic arthritis: a review of 46 cases. Ann Rheum Dis. 1980 Apr;39(2):129-34.
PubMed
Jonard PP, Rambaud JC, Dive C, Vaerman JP, Galian A, Delacroix DL: Secretion of immunoglobulins and plasma proteins from the jejunal mucosa. Transport rate and origin of polymeric immunoglobulin A. J Clin Invest. 1984 Aug;74(2):525-35.
PubMed
Variant
0.1 mg
11-947-C100
In stock
140.00 USD
Variant
0.1 mg
11-947-C100
In stock
140.00 USD
Contact distributor
Datasheet download
SDS download
CS
EN
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Technical support for this product
Related products
11-632-C100
Mouse IgG1 Isotype Control Purified
-134%
Clone
MOPC-21
Reg. status
RUO
Application
ELISA, FC, FC(IC), IP, WB, IHC(F), IHC(P), ICC
0.1 mg
105.00 USD
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