Anti-Hu Ig Lambda Light Chain Purified

Anti-Hu Ig Lambda Light Chain Purified
Regulatory status
RUO
Antigen
Ig Lambda Light Chain
Clone
4C2
Format
Purified
Reactivity
Human
Variant
0.1 mg
11-505-C100
In stock
150.00 USD

0.025 mg
11-505-C025
Delivery 1 week
75.00 USD
Variant
0.1 mg
11-261-C100
In stock
150.00 USD

0.1 mg
11-261-C100
In stock
75.00 USD
Product details
Description
Images
References
Isotype
Mouse IgG1
Specificity
The antibody 4C2 reacts with lambda light chains (22.5 kDa) of human immunoglobulin.
Application details
Flow cytometry: Recommended dilution: 2-8 μg/ml; positive control: RAMOS human cell line.
Reactivity
Human
Negative species
Rabbit, Hamster, Sheep, Guinea pig, Goat
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
Immunoglobulin lambda, Igl
Antigen description
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
11-505 FC
Flow cytometry analysis (surface staining) of human peripheral blood with anti-human lambda light chain (4C2) purified, GAM-APC.

General references:

Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95.
PubMed

Product specific references:

Os A, Bürgler S, Ribes AP, Funderud A, Wang D, Thompson KM, Tjønnfjord GE, Bogen B, Munthe LA: Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells. Cell Rep. 2013 Aug 15;4(3):566-77.
PubMed
Variant
0.1 mg
11-505-C100
In stock
150.00 USD

0.025 mg
11-505-C025
Delivery 1 week
75.00 USD
Variant
0.1 mg
11-261-C100
In stock
150.00 USD

0.1 mg
11-261-C100
In stock
75.00 USD

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