Anti-Hu Ig Lambda Light Chain PE

Anti-Hu Ig Lambda Light Chain PE
Regulatory status
RUO
Antigen
Ig Lambda Light Chain
Clone
1-155-2
Format
PE
Reactivity
Human
Application
FC (QC tested)
Excitation laser
blue (488 nm)
Variant
100 tests
1P-673-T100
In stock
220.00 USD

25 tests
1P-673-T025
In stock
110.00 USD
Variant
0.1 mg
11-261-C100
In stock
220.00 USD

0.1 mg
11-261-C100
In stock
110.00 USD
Product details
Images
References
Isotype
Mouse IgG1 kappa
Specificity
The mouse monoclonal antibody 1-155-2 recognizes lambda light chains (22.5 kDa) of human immunoglobulin.
Application
FC (QC tested)
Application details
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity
Human
Immunogen
Human IgA1 lambda myeloma protein
Other names
Immunoglobulin lambda, Igl
Preparation
The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
1P-673_FC_Profil Značení
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human Ig Lambda Light Chain (1-155-2) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).
1P-673_FC_Dot-plot
Flow cytometry multicolor surface staining of human lymphocytes stained using anti-human Ig Lambda Light Chain (1-155-2) PE antibody (10 μl reagent / 100 μl of peripheral whole blood) and anti-human CD19 (LT19) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
1P-673_FC_Histogram
Separation of human Ig Lambda Light Chain positive B cells (red-filled) from Ig Lambda Light Chain negative B cells (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human Ig Lambda Light Chain (1-155-2) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).

General references:

Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95.
PubMed

Product specific references:

Kubagawa H, Gathings WE, Levitt D, Kearney JF, Cooper MD: Immunoglobulin isotype expression of normal pre-B cells as determined by immunofluorescence. J Clin Immunol. 1982 Oct;2(4):264-9.
PubMed
Bahler DW, Pindzola JA, Swerdlow SH: Splenic marginal zone lymphomas appear to originate from different B cell types. Am J Pathol. 2002 Jul;161(1):81-8.
PubMed
Tierens AM, Holte H, Warsame A, Ikonomou IM, Wang J, Chan WC, Delabie J: Low levels of monoclonal small B cells in the bone marrow of patients with diffuse large B-cell lymphoma of activated B-cell type but not of germinal center B-cell type. Haematologica. 2010 Aug;95(8):1334-41.
PubMed
Variant
100 tests
1P-673-T100
In stock
220.00 USD

25 tests
1P-673-T025
In stock
110.00 USD
Variant
0.1 mg
11-261-C100
In stock
220.00 USD

0.1 mg
11-261-C100
In stock
110.00 USD

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