Exbio — Research products — Antibodies — Serum, plasma, and secreted proteins — Anti-Hu Ig Kappa Light Chain Purified

Anti-Hu Ig Kappa Light Chain Purified

Anti-Hu Ig Kappa Light Chain Purified
Regulatory status
RUO
Antigen
Ig Kappa Light Chain
Clone
A8B5
Format
Purified
Reactivity
Human
Application
ELISA, FC (QC tested), IHC(F), IHC(P)
Variant
0.1 mg
11-504-C100
In stock
150.00 USD
0.025 mg
11-504-C025
Delivery 1 week
75.00 USD
Variant
0.1 mg
11-261-C100
In stock
150.00 USD
0.1 mg
11-261-C100
In stock
75.00 USD
Contact distributor
Product details
Description
References
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody A8B5 reacts with kappa light chains (22.5 kDa) of immunoglobulins.
Application
ELISA, FC (QC tested), IHC(F), IHC(P)
Application details
Flow cytometry: Recommended dilution: 1-4 µg/ml, Positive control: Daudi human cell line.
Reactivity
Human
Negative species
Rabbit, Hamster, Sheep, Guinea pig, Goat
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
Immunoglobulin kappa, Igk
Antigen description
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.

General references:

Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95.
PubMed

Product specific references:

Diaz de Domingo NB, Lardo MM, Romero Artaza J, Merelli A, Carbia CD, Sánchez Avalos JC: Aplicacion de tecnicas inmunocitoquimicas para el diagnostico de neoplasias hematologicas. Medicina (B Aires). 1999;59(1):11-6.
PubMed
Scheeren FA, Diehl SA, Smit LA, Beaumont T, Naspetti M, Bende RJ, Blom B, Karube K, Ohshima K, van Noesel CJ, Spits H: IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis. Blood. 2008 May 1;111(9):4706-15. doi: 10.1182/blood-2007-08-105643
PubMed
Di Bartolo DL, Hyjek E, Keller S, Guasparri I, Deng H, Sun R, Chadburn A, Knowles DM, Cesarman E: Role of defective Oct-2 and OCA-B expression in immunoglobulin production and Kaposi's sarcoma-associated herpesvirus lytic reactivation in primary effusion lymphoma. J Virol. 2009 May;83(9):4308-15. doi: 10.1128/JVI.02196-08.
PubMed
Konig A, Wennemuth G, Soyer HP, Hoffmann R, Happle R, Krause W: Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma. Eur J Dermatol. 1999 Jan-Feb;9(1):29-31.
PubMed
Avilés-Salas A, Chanona-Vilchis JG, Candelaria-Hernández MG, Peña-Torres Mde L, Cuéllar-Mendoza ME: Presentación inicial de un linfoma plasmablástico como tumor ovárico. Ginecol Obstet Mex. 2012 Jun;80(6):430-4.
PubMed
Variant
0.1 mg
11-504-C100
In stock
150.00 USD
0.025 mg
11-504-C025
Delivery 1 week
75.00 USD
Variant
0.1 mg
11-261-C100
In stock
150.00 USD
0.1 mg
11-261-C100
In stock
75.00 USD
Contact distributor
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