Anti-Hu Ig Kappa Light Chain Pacific Blue™

Anti-Hu Ig Kappa Light Chain Pacific Blue™
Regulatory status
RUO
Antigen
Ig Kappa Light Chain
Clone
A8B5
Format
Pacific Blue™
Reactivity
Human
Application
FC (QC tested)
Excitation laser
violet (405 nm)
Variant
100 tests
PB-504-T100
In stock

25 tests
PB-504-T025
In stock
Variant
0.1 mg
11-261-C100
In stock

0.1 mg
11-261-C100
In stock
Product details
Images
References
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody A8B5 reacts with kappa light chains (22.5 kDa) of immunoglobulins.
Application
FC (QC tested)
Application details
Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Reactivity
Human
Negative species
Rabbit, Hamster, Sheep, Guinea pig, Goat
Other names
Immunoglobulin kappa, Igk
Preparation
The purified antibody is conjugated with Pacific Blue™ under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
Unless indicated otherwise, all products are For Research Use Only and not for diagnostic use. In vivo diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s. © 2019 EXBIO Praha, a.s. All rights reserved.
Licence note
Alexa Fluor®, Pacific Blue™ and Pacific Orange™ are registered trademarks of Life Technologies Corporation.
Licence label
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchsing a license to this product for purposes orther than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com.
PB-504 FC
Flow cytometry analysis (surface staining) of immunoglobulin kappa light chains in human peripheral blood with anti-kappa light chains (A8B5) Pacific BlueTM.

General references:

Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95.
PubMed

Product specific references:

Diaz de Domingo NB, Lardo MM, Romero Artaza J, Merelli A, Carbia CD, Sánchez Avalos JC: Aplicacion de tecnicas inmunocitoquimicas para el diagnostico de neoplasias hematologicas. Medicina (B Aires). 1999;59(1):11-6.
PubMed
Scheeren FA, Diehl SA, Smit LA, Beaumont T, Naspetti M, Bende RJ, Blom B, Karube K, Ohshima K, van Noesel CJ, Spits H: IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis. Blood. 2008 May 1;111(9):4706-15. doi: 10.1182/blood-2007-08-105643
PubMed
Di Bartolo DL, Hyjek E, Keller S, Guasparri I, Deng H, Sun R, Chadburn A, Knowles DM, Cesarman E: Role of defective Oct-2 and OCA-B expression in immunoglobulin production and Kaposi's sarcoma-associated herpesvirus lytic reactivation in primary effusion lymphoma. J Virol. 2009 May;83(9):4308-15. doi: 10.1128/JVI.02196-08.
PubMed
Konig A, Wennemuth G, Soyer HP, Hoffmann R, Happle R, Krause W: Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma. Eur J Dermatol. 1999 Jan-Feb;9(1):29-31.
PubMed
Avilés-Salas A, Chanona-Vilchis JG, Candelaria-Hernández MG, Peña-Torres Mde L, Cuéllar-Mendoza ME: Presentación inicial de un linfoma plasmablástico como tumor ovárico. Ginecol Obstet Mex. 2012 Jun;80(6):430-4.
PubMed
Variant
100 tests
PB-504-T100
In stock

25 tests
PB-504-T025
In stock
Variant
0.1 mg
11-261-C100
In stock

0.1 mg
11-261-C100
In stock