Exbio — Research products — Antibodies — Serum, plasma, and secreted proteins — Anti-Hu C-peptide Purified

Anti-Hu C-peptide Purified

Regulatory status

RUO

Antigen

C-peptide

Clone

C-PEP-01

Format

Purified

Reactivity

Human

Application

ELISA, RIA, IHC-P, ICC

Variant

0.1 mg

11-247-C100

In stock

143.00 USD

0.025 mg

11-247-C025

Delivery 1 week

71.50 USD

Variant

0.1 mg

11-247-C100

In stock

143.00 USD

0.025 mg

11-247-C025

Delivery 1 week

71.50 USD

Contact distributor

Product details

Description

Images

References

SDS download

Isotype

Mouse IgG1

Specificity

The mouse monoclonal antibody C-PEP-01 reacts specifically with C-peptide, a part of the proinsulin molecule. Proinsulin consists of three parts: C-peptide and two long strands of amino acids (alpha and beta chains; later become linked together to form the insulin molecule). No cross-reactivity with insulin or other peptide hormones or proteins was observed.

Application

ELISA, RIA, IHC-P, ICC

Application details

Immunohistochemistry (paraffin sections): Recommended dilution: 2-5 μg/ml; positive control: human pancreas (islets of Langerhans).

Reactivity

Human

Immunogen

Human C-peptide conjugated to bovine serum albumin.

Concentration

1 mg/ml

Preparation

Purified by protein-A affinity chromatography.

Formulation

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Other names

C-peptide of proinsulin

Antigen description

From every molecule of proinsulin, one molecule of insulin plus one molecule of C-peptide are produced. C-peptide is released into the blood stream in equal amounts to insulin.

Immunohistochemistry staining of human pancreas (paraffin-embedded sections) with anti-human to C-peptide of Proinsulin (C-PEP-01).

Product specific references:

Hilgert I, Stolba P, Kristofova H, Stefanova I, Bendlova B, Lebl M, Horejsi V: A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA. Hybridoma. 1991 Jun;10(3):379-86.
PubMed

Quardokus EM, Saunders DC, McDonough E, Hickey JW, Werlein C, Surrette C, Rajbhandari P, Martinez Casals A, Tian H, Lowery L, Neumann EK, Björklund F, Neelakantan TV, Croteau J, Wiblin AE, Fisher J, Livengood AJ, Dowell KG, Silverstein JC, Spraggins JM, Pryhuber GS, Deutsch G, Ginty F, Nolan GP, Melov S, Jonigk D, Caldwell MA, Vlachos IS, Mueller W, Gehlenborg N, Stockwell BR, Lundberg E, Snyder MP, Germain RN, Camarillo JM, Kelleher NL, Börner K, Radtke AJ: Organ mapping antibody panels: a community resource for standardized multiplexed tissue imaging. Nat Methods 2023 Aug;20(8):1174-1178. doi: 10.1038/s41592-023-01846-7.
PubMed