Exbio — Research products — Antibodies — Serum, plasma, and secreted proteins — Anti-hTSH Purified

Anti-hTSH Purified

Regulatory status

RUO

Antigen

hTSH

Clone

TSH-51

Format

Purified

Reactivity

Human

Application

ELISA, RIA, ICC

Variant

0.1 mg

11-124-C100

In stock

121.00 USD

0.025 mg

11-124-C025

Delivery 1 week

60.50 USD

Variant

0.1 mg

11-124-C100

In stock

121.00 USD

0.025 mg

11-124-C025

Delivery 1 week

60.50 USD

Contact distributor

Product details

Description

References

SDS download

Isotype

Mouse IgG2a

Specificity

The antibody TSH-51 reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain. The TSH-51 antibody reacts with association constant 5.5 x 10¹⁰ l/mol. Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-51: hTSH (68.6), hCG (0.03), hLH (2.99), hFSH (0.66).

Application

ELISA, RIA, ICC

Application details

RIA: The antibody TSH-51 is suitable in combination with the antibody TSH-116 for immunometric assays in the screening of neonatal hypothyroidism.

Reactivity

Human

Immunogen

Human thyrotropin.

Concentration

1 mg/ml

Preparation

Purified by protein-A affinity chromatography.

Formulation

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Other names

Thyrotropin

Antigen description

Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones. hTSH is composed of two subunits - alpha nad beta.

Product specific references:

Jirkalová V, Čáp J, Straková H, Přibyšová J, Plicka J, Lomský R: Immunoradiometric and luminescence immunoenzymometric assay of human thyrotropin from dried blood spots for screening of neonatal hypothyroidism. Eur J Clin Chem Clin Biochem. 1996 Oct;34(10):823-7.
PubMed