Anti-UBN1 Purified

Anti-UBN1 Purified
Regulatory status
RUO
Antigen
UBN1
Clone
UBN1-02
Format
Purified
Reactivity
Human
Application
IP, WB
Variant
0.1 mg
11-565-C100
In stock
180.00 USD

0.025 mg
11-565-C025
Out of stock
90.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD

0.1 mg
11-261-C100
In stock
90.00 USD
Product details
Images
References
Isotype
Mouse IgG
Specificity
The antibody UBN1-02 recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.
Application
IP, WB
Reactivity
Human
Immunogen
Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1.
Other names
Ubinuclein 1, VT4
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
11-565 WB
Western blotting analysis of ubinuclein in nuclear fraction of HeLa cells. The monoclonal antibody UBN1-01 (lane A, B) detects ubinuclein 1 (165 kDa) and an 180 kDa protein - presumable ubinuclein 2. The antibody UBN1-02 (lane C, D) detects ubinuclein 1. Antibody dilution: A, C - 1 μg/ml; B, D - 5 μg/ml.

General references:

Aho S, Buisson M, Pajunen T, Ryoo YW, Giot JF, Gruffat H, Sergeant A, Uitto J: Ubinuclein, a novel nuclear protein interacting with cellular and viral transcription factors. J Cell Biol. 2000 Mar 20;148(6):1165-76.
PubMed
Aho S, Lupo J, Coly PA, Sabine A, Castellazzi M, Morand P, Sergeant A, Manet E, Boyer V, Gruffat H: Characterization of the ubinuclein protein as a new member of the nuclear and adhesion complex components (NaCos). Biol Cell. 2008 Sep 30.
PubMed
Banumathy G, Somaiah N, Zhang R, Tang Y, Hoffmann J, Andrake M, Ceulemans H, Schultz D, Marmorstein R, Adams PD: Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells. Mol Cell Biol. 2009 Feb;29(3):758-70.
PubMed
Variant
0.1 mg
11-565-C100
In stock
180.00 USD

0.025 mg
11-565-C025
Out of stock
90.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD

0.1 mg
11-261-C100
In stock
90.00 USD