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Exbio
—
Research products
—
Antibodies
—
Nucleus
—
Anti-p63 Purified
Anti-p63 Purified
Regulatory status
RUO
Antigen
p63
Clone
PANp63-6.1
Format
Purified
Reactivity
Mouse, Rat, Human
Application
IP, WB, IHC(P), ICC
Variant
0.1 mg
11-888-C100
In stock
198.00 USD
Variant
0.1 mg
11-888-C100
In stock
198.00 USD
Contact distributor
Product details
Description
Images
References
SDS download
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody PANp63-6.1 recognizes both TAp63, and deltaNp63 form of p63. The target epitope PSHLIR is located within amino acids 261-266 of TAp63, and 167-172 of deltaNp63.
Application
IP, WB, IHC(P), ICC
Application details
Western blotting: Recommended dilution: 1 μg/ml
Reactivity
Mouse, Rat, Human
Immunogen
Recombinant full length human p63
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
TAp63 + deltaNp63, AIS, KET, LMS, NBP, RHS, EEC3, OFC8, SHFM4
Antigen description
The p53 family of proteins includes three members, p53, p63, and p73. The protein p63 is encoded by TP63 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp63) or absence (deltaNp63) of an N-terminal transactivation domain. Immunohistochemistry of p63 has a clinical relevance for certain tumor types, but investigations have been hampered by a lack of well characterized antibodies that are specific for p63 and do not cross-react with the related p53 and p73 proteins.
Entrez Gene ID
8626
UniProt ID
Q9H3D4
Western blotting analysis of p63 isoforms using mouse monoclonal antibody PANp63.1. This antibody detects both TAp63 and deltaNp63 isoforms, as demonstrated on particular transfectants.
Product specific references:
Nekulová M, Holčáková J, Nenutil R, Stratmann R, Bouchalová P, Müller P, Mouková L, Coates PJ, Vojtěšek B: Characterization of specific p63 and p63-N-terminal isoform antibodies and their application for immunohistochemistry. Virchows Arch. 2013 Sep;463(3):415-25.
PubMed
Further SDS language mutations available for download below. Please contact us with request for additional languages on info@exbio.cz
MPAbNaN3_SDS_v1_AU.pdf
MPAbNaN3_SDS_v1_GB.pdf
MPAbNaN3_SDS_v1_TR.pdf
MPAbNaN3_SDS_v6_AT.pdf
MPAbNaN3_SDS_v6_CH.pdf
MPAbNaN3_SDS_v6_CS.pdf
MPAbNaN3_SDS_v6_EN.pdf
MPAbNaN3_SDS_v6_ES.pdf
MPAbNaN3_SDS_v6_FR.pdf
MPAbNaN3_SDS_v6_IT.pdf
MPAbNaN3_SDS_v6_NO.pdf
MPAbNaN3_SDS_v6_PL.pdf
MPAbNaN3_SDS_v6_PT.pdf
MPAbNaN3_SDS_v6_SE.pdf
MPAbNaN3_SDS_v6_SK.pdf
MPAbNaN3_SDS_v6_SL.pdf
MPAbNaN3_SDS_v7_DE.pdf
Variant
0.1 mg
11-888-C100
In stock
198.00 USD
Variant
0.1 mg
11-888-C100
In stock
198.00 USD
Contact distributor
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