Anti-Notch1 APC

Anti-Notch1 APC
Regulatory status
RUO
Antigen
Notch1
Clone
mN1A
Format
APC
Reactivity
Mouse, Human
Application
FC (QC tested)
Excitation laser
red (633 nm)
Variant
0.1 mg
1A-651-C100
Out of stock
180.00 USD

0.025 mg
1A-651-C025
Out of stock
90.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD

0.1 mg
11-261-C100
In stock
90.00 USD
Product details
Images
References
Isotype
Mouse IgG1 kappa
Specificity
The mouse monoclonal antibody mN1A recognizes intracellular domain of Notch 1 protein, mainly its activated form. The unprocessed Notch 1 protein is recognized with lower affinity.
Application
FC (QC tested)
Reactivity
Mouse, Human
Negative species
Rat
Immunogen
GST fusion protein containing cdc10-NCR region of mouse Notch1
Other names
AOS5, TAN1, hN1, AOVD1
Concentration
0.1 mg/ml
Preparation
The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
1A-651 FC
Separation of MOLT-4 cell line (red) from Leukocytes(blue) in flow cytometry analysis (intracellular staining) stained using anti-human Notch1 (mN1A) APC antibody (concentration in sample 3 μg/ml).

Product specific references:

Khwaja SS, Liu H, Tong C, Jin F, Pear WS, van Deursen J, Bram RJ: HIV-1 Rev-binding protein accelerates cellular uptake of iron to drive Notch-induced T cell leukemogenesis in mice. J Clin Invest. 2010 Jul 1;120(7):2537-48.
PubMed
Sun H, Li L, Vercherat C, Gulbagci NT, Acharjee S, Li J, Chung TK, Thin TH, Taneja R: Stra13 regulates satellite cell activation by antagonizing Notch signaling. J Cell Biol. 2007 May 21;177(4):647-57.
PubMed
Variant
0.1 mg
1A-651-C100
Out of stock
180.00 USD

0.025 mg
1A-651-C025
Out of stock
90.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD

0.1 mg
11-261-C100
In stock
90.00 USD