Anti-Hu deltaNp73 Purified

Anti-Hu deltaNp73 Purified
Regulatory status
RUO
Antigen
deltaNp73
Clone
DNp73-1.1
Format
Purified
Reactivity
Human
Application
Variant
0.1 mg
11-889-C100
In stock
180.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD
Product details
Description
Images
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody DNp73-1.1 recognizes human deltaNp73; target epitope is MLYVGDPARHLAT.
Application
Application details
Western blotting: Recommended dilution: 1 μg/ml
Reactivity
Human
Immunogen
KLH-coupled synthetic peptide MLYVGDPARHLATC
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
p73 DN
Antigen description
The p53 family of proteins includes three members, p53, p63, and p73. The protein p73 is encoded by TP73 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp73) or absence (deltaNp73) of an N-terminal transactivation domain. Investigations have been hampered by a lack of well characterized antibodies that are specific for p73 and do not cross-react with the related p53 and p63 proteins, as well as a lack of antibodies that specifically recognize either the TAp73 or deltaNp73 variants. We are introducing now such a set of antibodies.
Entrez Gene ID 7161
UniProt ID O15350
11-889_WB
Western blotting analysis of p73 isoforms using mouse monoclonal antibody DNp73-1.1. This antibody is suitable for distinguishing between them. It detected specifically deltaNp73 isoform in H1299/deltaNp73 transfectants, whereas it ignored TAp73 isoform in H1299/TAp73 transfectants.
Variant
0.1 mg
11-889-C100
In stock
180.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD