Anti-Hu beta2-Microglobulin Biotin

Anti-Hu beta2-Microglobulin Biotin
Regulatory status
RUO
Antigen
beta2-Microglobulin
Clone
B2M-02
Format
Biotin
Reactivity
Pig, Human
Variant
0.1 mg
1B-456-C100
In stock
198.00 USD

0.025 mg
1B-456-C025
Delivery 1 week
99.00 USD
Variant
0.1 mg
1B-456-C100
In stock
198.00 USD

0.025 mg
1B-456-C025
Delivery 1 week
99.00 USD
Product details
Description
Images
References
SDS download
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody B2M-02 reacts with beta2-microglobulin (beta2M), an extracellular antigen associated with cell-surface MHC Class I molecules and other membrane antigens, as well as it reacts with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.
Application details
Flow cytometry: Recommended dilution: 1-2 μg/ml; positive control: PBL cell line, negative control: DAUDI human lymphoma cell line, erythrocytes.
Reactivity
Pig, Human
Immunogen
Purified isolated human beta2-microglobulin.
Concentration
1 mg/ml
Preparation
Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
B2M
Antigen description
Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.
Entrez Gene ID 567
UniProt ID P61769
1B-456 FC
Flow cytometry (surface staining) of human peripheral blood cells by mouse monoclonal anti-beta2-microglobulin antibody B2M-02 biotin.
1B-456 FC_2
Flow cytometry (surface staining) of human peripheral blood cells by mouse monoclonal anti-beta2-microglobulin antibody B2M-02 biotin.

Product specific references:

Drbal K, Angelisova P, Hilgert I, Cerny J, Novak P, Horejsi V: A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells. Blood. 2001 Sep 1;98(5):1561-6.
PubMed
Hilgert I, Horejsi V, Kristofova H: The use of murine monoclonal antibody B2M-01 for detection and purification of human beta 2-microglobulin. Folia Biol (Praha). 1984;30(6):369-76.
PubMed
Variant
0.1 mg
1B-456-C100
In stock
198.00 USD

0.025 mg
1B-456-C025
Delivery 1 week
99.00 USD
Variant
0.1 mg
1B-456-C100
In stock
198.00 USD

0.025 mg
1B-456-C025
Delivery 1 week
99.00 USD