Exbio — Research products — Antibodies — MHC antigens — Anti-HLA-G FITC

Anti-HLA-G FITC

Anti-HLA-G FITC
Regulatory status
RUO
Antigen
HLA-G
Clone
MEM-G/11
Format
FITC
Reactivity
Human
Application
FC (QC tested)
Excitation laser
blue (488 nm)
Variant
0.1 mg
1F-389-C100
In stock
260.00 USD
0.025 mg
1F-389-C025
Out of stock
130.00 USD
Variant
0.1 mg
11-261-C100
In stock
260.00 USD
0.1 mg
11-261-C100
In stock
130.00 USD
Contact distributor
Product details
References
Isotype
Mouse IgG1
Specificity
The antibody MEM-G/11 recognizes an extracellular epitope of HLA-G1 antigen. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.
Application
FC (QC tested)
Application details
Flow cytometry: The antibody MEM-G/11 does not cross-block standard MEM-G/9 antibody. Recommended dilution: 1-3 μg/ml.
Reactivity
Human
Immunogen
Recombinant human HLA-G refolded with beta2-microglobulin and peptide.
Concentration
1 mg/ml
Preparation
The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

General references:

Creput C, Durrbach A, Menier C, Guettier C, Samuel D, Dausset J, Charpentier B, Carosella ED, Rouas-Freiss N. Human leukocyte antigen-G (HLA-G) expression in biliary epithelial cells is associated with allograft acceptance in liver-kidney transplantation. J Hepatol. 2003 39(4):587-94.
PubMed
Menier C, Saez B, Horejsi V, Martinozzi S, Krawice-Radanne I, Bruel S, LeDanff C, Reboul M, Hilgert I, Rabreau M, Larrad ML, Pla M, Carosella ED, Rouas-Freiss N: Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules. Hum Immunol. 2003 64(3):315-26.
PubMed

Product specific references:

Boyson JE, Erskine R, Whitman MC, Chiu M, Lau JM, Koopman LA, Valter MM, Angelisova P, Horejsi V, Strominger JL.: Disulfide bond-mediated dimerization of HLA-G on the cell surface. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16180-5.
PubMed
Variant
0.1 mg
1F-389-C100
In stock
260.00 USD
0.025 mg
1F-389-C025
Out of stock
130.00 USD
Variant
0.1 mg
11-261-C100
In stock
260.00 USD
0.1 mg
11-261-C100
In stock
130.00 USD
Contact distributor
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SDS download
Bulk requests
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