Anti-HLA Class I PE

Anti-HLA Class I PE
Regulatory status
RUO
Antigen
HLA Class I
Clone
MEM-123
Format
PE
Reactivity
Cow, Human, Non-human primates
Application
Excitation laser
blue (488 nm)
Variant
0.1 mg
1P-363-C100
In stock
286.00 USD

0.025 mg
1P-363-C025
Delivery 1 week
143.00 USD
Variant
0.1 mg
1P-363-C100
In stock
286.00 USD

0.025 mg
1P-363-C025
Delivery 1 week
143.00 USD
Product details
Description
Images
SDS download
Isotype
Mouse IgG3
Specificity
The antibody MEM-123 reacts with an extracellular epitope of all human classical MHC Class I molecules (major histocompatibility complex) in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. The antibody MEM-123 completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks the antibody MEM-G/9.
Application
Application details
Flow cytometry: Recommended dilution: 2-4 μg/ml.
Reactivity
Cow, Human, Non-human primates
Immunogen
COS-7 African green monkey kidney cells
Concentration
0.1 mg/ml
Preparation
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Antigen description
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
1P-363 FC
Flow cytometry analysis (surface staining) of K562 cells with anti-HLA-class I (MEM-123) PE.
Variant
0.1 mg
1P-363-C100
In stock
286.00 USD

0.025 mg
1P-363-C025
Delivery 1 week
143.00 USD
Variant
0.1 mg
1P-363-C100
In stock
286.00 USD

0.025 mg
1P-363-C025
Delivery 1 week
143.00 USD

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