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Exbio
—
Research products
—
Antibodies
—
Cytoskeleton and ECM
—
Anti-Kinesin Purified
Anti-Kinesin Purified
Regulatory status
RUO
Antigen
Kinesin
Clone
PAb (434)
Format
Purified
Reactivity
Mouse, Pig, Human
Application
WB, ICC
Variant
0.1 mg
11-434-C100
In stock
180.00 USD
0.025 mg
11-434-C025
Delivery 1 week
90.00 USD
Variant
0.1 mg
11-434-C100
In stock
180.00 USD
0.025 mg
11-434-C025
Delivery 1 week
90.00 USD
Contact distributor
Product details
Description
Images
References
SDS download
Isotype
Rabbit polyclonal
Specificity
The polyclonal antibody detects total level of endogenous kinesin protein (intracellular antigen).
Application
WB, ICC
Reactivity
Mouse, Pig, Human
Immunogen
stalk domain of human kinesin (aa 331-906) expressed in
E. coli
(FKHC3)
Concentration
1 mg/ml
Preparation
Purified by ligand affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
KIN
Antigen description
Kinesin belongs to the group of microtubule-associated motor proteins known to convert chemical energy released from nucleoside triphosphates (preferentially from ATP) into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport in neuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120 to 130 kDa) and two light chains (60 to 70 kDa), resulting in a molecular mass about 400 kDa. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function.
Western blotting detection of kinesin in reduced lysates of human HEK cell line (1) and porcine brain (2) by rabbit polyclonal anti-kinesin.
Product specific references:
Malcova-Janatova I, Richterova V, Draber P, Hasek J: Preparation of human recombinant kinesin heavy chain and epitope mapping of its structural domains. Folia Microbiol (Praha). 2004;49(6):665-70.
PubMed
Further SDS language mutations available for download below. Please contact us with request for additional languages on info@exbio.cz
MPAbNaN3_SDS_v1_AU.pdf
MPAbNaN3_SDS_v1_GB.pdf
MPAbNaN3_SDS_v1_TR.pdf
MPAbNaN3_SDS_v6_CH.pdf
MPAbNaN3_SDS_v6_CS.pdf
MPAbNaN3_SDS_v6_EN.pdf
MPAbNaN3_SDS_v6_ES.pdf
MPAbNaN3_SDS_v6_FR.pdf
MPAbNaN3_SDS_v6_IT.pdf
MPAbNaN3_SDS_v6_NO.pdf
MPAbNaN3_SDS_v6_PL.pdf
MPAbNaN3_SDS_v6_PT.pdf
MPAbNaN3_SDS_v6_SE.pdf
MPAbNaN3_SDS_v6_SK.pdf
MPAbNaN3_SDS_v7_DE.pdf
Variant
0.1 mg
11-434-C100
In stock
180.00 USD
0.025 mg
11-434-C025
Delivery 1 week
90.00 USD
Variant
0.1 mg
11-434-C100
In stock
180.00 USD
0.025 mg
11-434-C025
Delivery 1 week
90.00 USD
Contact distributor
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