Exbio — Research products — Antibodies — Cytoskeleton and ECM — Anti-Cytokeratin 10 Purified

Anti-Cytokeratin 10 Purified

Regulatory status

RUO

Antigen

Cytokeratin 10

Clone

VIK-10

Format

Purified

Reactivity

Human

Application

IP, IHC-P, ICC

Variant

0.1 mg

11-111-C100

In stock

143.00 USD

0.025 mg

11-111-C025

Delivery 1 week

71.50 USD

Variant

0.1 mg

11-111-C100

In stock

143.00 USD

0.025 mg

11-111-C025

Delivery 1 week

71.50 USD

Contact distributor

Product details

Description

Images

References

SDS download

Isotype

Mouse IgG1

Specificity

The antibody VIK-10 reacts with cytokeratin 10 (56.5 kDa; intracellular antigen). Cytokeratins are members of intermediate filaments subfamily represented in epithelial tissues.

Application

IP, IHC-P, ICC

Application details

Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/ml; positive tissue: skin, pretreatment: trypsin/temperature 37 °C.

Reactivity

Human

Immunogen

Cytoskeleton preparation extracted from human epidermis by detergent/high salt extraction.

Concentration

1 mg/ml

Preparation

Purified by protein-A affinity chromatography.

Formulation

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Other names

BIE, EHK, K10, KPP, BCIE, CK10, CK-10, CYK10, KRT10

Antigen description

Cytokeratins are a subfamily of intermediate filaments and are characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.

Entrez Gene ID 3858

UniProt ID P13645

Immunohistochemistry staining of skin basaliom (paraffin-embedded sections) with anti-human Cytokeratin 10 (VIK-10).

Product specific references:

Ivanyi D, Minke JM, Hageman C, Groeneveld E, van Doornewaard G: Patterns of expression of feline cytokeratins in healthy epithelia and mammary carcinoma cells. Am J Vet Res. 1992 Mar;53(3):304-14.
PubMed