Exbio — Research products — Antibodies — Cytoskeleton and ECM — Anti-Basic Cytokeratins Purified

Anti-Basic Cytokeratins Purified

Anti-Basic Cytokeratins Purified
Regulatory status
RUO
Antigen
Basic Cytokeratins
Clone
AE3
Format
Purified
Reactivity
Cow, Rabbit, Mouse, Human, Non-human primates, Chicken, Rat
Application
WB, IHC(F), IHC(P)
Variant
0.1 mg
11-769-C100
In stock
0.025 mg
11-769-C025
Out of stock
Variant
0.1 mg
11-261-C100
In stock
0.1 mg
11-261-C100
In stock
Contact us
Product details
References
Isotype
Mouse IgG1
Specificity
Mouse monoclonal antibody AE3 recognizes all basic type cytokeratins, namely K1-K8 (58-67 kDa). This antibody reacts with all layers of epidermis (basal layer and above) and is an excellent marker for distinguishing carcinomas from non-epithelial tumours.
Application
WB, IHC(F), IHC(P)
Reactivity
Cow, Rabbit, Mouse, Human, Non-human primates, Chicken, Rat
Immunogen
Human epidermal keratins
Other names
Type II cytokeratins
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Exbio licence note
Unless indicated otherwise, all products are For Research Use Only and not for diagnostic use. In vivo diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s. © 2019 EXBIO Praha, a.s. All rights reserved.

Product specific references:

Hunt RC, Davis AA: Altered expression of keratin and vimentin in human retinal pigment epithelial cells in vivo and in vitro. J Cell Physiol. 1990 Nov;145(2):187-99.
PubMed
Woodcock-Mitchell J, Eichner R, Nelson WG, Sun TT: Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies. J Cell Biol. 1982 Nov;95(2 Pt 1):580-8.
PubMed
Zhang B, Chen Y, Han Z, Ris H, Zhai Z: The role of keratin filaments during nuclear envelope reassembly in Xenopus egg extracts. FEBS Lett. 1998 May 22;428(1-2):52-6.
PubMed
Yeh IT, Miller AR: Staining of sentinel node reticulum cells with cytokeratin antibody AE3. Arch Pathol Lab Med. 2002 Mar;126(3):248-9.
PubMed
Listrom MB, Dalton LW: Comparison of keratin monoclonal antibodies MAK-6, AE1:AE3, and CAM-5.2. Am J Clin Pathol. 1987 Sep;88(3):297-301.
PubMed
Variant
0.1 mg
11-769-C100
In stock
0.025 mg
11-769-C025
Out of stock
Variant
0.1 mg
11-261-C100
In stock
0.1 mg
11-261-C100
In stock
Contact us
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SDS download
Bulk requests
Technical support for this product