Anti-Ms CD49d PE

Anti-Ms CD49d PE
Regulatory status
RUO
Antigen
CD49d
Clone
R1-2
Format
PE
Reactivity
Mouse
Application
FC (QC tested)
Excitation laser
blue (488 nm)
Variant
0.1 mg
1P-734-C100
In stock
120.00 USD

0.025 mg
1P-734-C025
Out of stock
Variant
0.1 mg
11-261-C100
In stock
120.00 USD

0.1 mg
11-261-C100
In stock
Product details
References
Isotype
Rat IgG2b kappa
Specificity
The rat monoclonal antibody R1-2 recognizes an extracellular epitope of murine CD49d / Integrin alpha 4 (VLA-4 alpha), an approximately 150 kDa glycoprotein of the integrin family, expressed on multiple blood cell types.
Application
FC (QC tested)
Reactivity
Mouse
Immunogen
murine T lymphoma line TK1
Other names
Itga4, Vla-4 alpha
Concentration
0.5 mg/ml
Preparation
The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Product specific references:

Zhu X, Nishimura F, Sasaki K, Fujita M, Dusak JE, Eguchi J, Fellows-Mayle W, Storkus WJ, Walker PR, Salazar AM, Okada H: Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models. J Transl Med. 2007 Feb 12;5:10.
PubMed
Sadahira Y, Yasuda T, Yoshino T, Manabe T, Takeishi T, Kobayashi Y, Ebe Y, Naito M: Impaired splenic erythropoiesis in phlebotomized mice injected with CL2MDP-liposome: an experimental model for studying the role of stromal macrophages in erythropoiesis. J Leukoc Biol. 2000 Oct;68(4):464-70.
PubMed
Cheung DS, Ehlenbach SJ, Kitchens RT, Riley DA, Thomas LL, Holtzman MJ, Grayson MH: Cutting edge: CD49d+ neutrophils induce FcepsilonRI expression on lung dendritic cells in a mouse model of postviral asthma. J Immunol. 2010 Nov 1;185(9):4983-7.
PubMed
Geutskens SB, Nikolic T, Dardenne M, Leenen PJ, Savino W: Defective up-regulation of CD49d in final maturation of NOD mouse macrophages. Eur J Immunol. 2004 Dec;34(12):3465-76.
PubMed
Lin J, Qin L, Chavin KD, Ding Y, Punch JD, Yang Q, Burkly LC, Bromberg JS: CD3 and CD2 ligation alters CD49d epitope expression. Pathobiology. 1995;63(3):119-32.
PubMed
Variant
0.1 mg
1P-734-C100
In stock
120.00 USD

0.025 mg
1P-734-C025
Out of stock
Variant
0.1 mg
11-261-C100
In stock
120.00 USD

0.1 mg
11-261-C100
In stock