Anti-Ms CD197 Purified

Anti-Ms CD197 Purified
Regulatory status
RUO
Antigen
CD197
Clone
4B12
Format
Purified
Reactivity
Mouse
Variant
0.1 mg
11-735-C100
In stock
176.00 USD

0.025 mg
11-735-C025
Delivery 1 week
88.00 USD
Variant
0.1 mg
11-735-C100
In stock
176.00 USD

0.025 mg
11-735-C025
Delivery 1 week
88.00 USD
Product details
Description
Images
References
SDS download
Isotype
Rat IgG2a kappa
Specificity
The rat monoclonal antibody 4B12 recognizes an extracellular epitope of murine CD197 / CCR7 (chemokine receptor 7), a 43 kDa G-protein-coupled receptor for chemokines CCL19 and CCL21.
Application details
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Reactivity
Mouse
Immunogen
Murine CD197-transfected RBL-2H3 cells
Concentration
1 mg/ml
Preparation
Purified by protein-G affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
CCR7, CC-CKR-7, EBI1
Antigen description
CD197 / CCR7 (chemokine receptor 7) is a seven membrane-spanning protein serving as a receptor for chemokines CCL19 and CCL21. It is expressed on most naive T cells, some hematopoietic stem cells, mature dendritic cells, NK cells and some memory T cells and B cells subsets. CD197 plays important roles in development of thymocytes, and regulating the recirculation and homing of lymphocytes and dendritic cells to secondary lymphoid organs.
Entrez Gene ID 12775
UniProt ID P47774
11-735 FC
Flow cytometry surface staining pattern of murine splenocytes stained using anti-mouse CD197 (4B12) purified antibody (concentration in sample 4 μg/ml, DAR APC, red) and murine splenocytes unstained by primary antibody (DAR APC, blue).

Product specific references:

Singh V, Gowthaman U, Jain S, Parihar P, Banskar S, Gupta P, Gupta UD, Agrewala JN: Coadministration of interleukins 7 and 15 with bacille Calmette-Guérin mounts enduring T cell memory response against Mycobacterium tuberculosis. J Infect Dis. 2010 Aug 15;202(3):480-9
PubMed
Adachi K, Osada Y, Nakamura R, Tamada K, Hamano S: Unique T cells with unconventional cytokine profiles induced in the livers of mice during schistosoma mansoni infection. PLoS One. 2013 Dec 16;8(12):e82698.
PubMed
Huggins A, Paschalidis N, Flower RJ, Perretti M, D'Acquisto F: Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation. FASEB J. 2009 Apr;23(4):985-96
PubMed
Eisenbarth SC, Williams A, Colegio OR, Meng H, Strowig T, Rongvaux A, Henao-Mejia J, Thaiss CA, Joly S, Gonzalez DG, Xu L, Zenewicz LA, Haberman AM, Elinav E, Kleinstein SH, Sutterwala FS, Flavell RA: NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells. Nature. 2012 Apr 25;484(7395):510-3
PubMed
Variant
0.1 mg
11-735-C100
In stock
176.00 USD

0.025 mg
11-735-C025
Delivery 1 week
88.00 USD
Variant
0.1 mg
11-735-C100
In stock
176.00 USD

0.025 mg
11-735-C025
Delivery 1 week
88.00 USD

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