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Exbio
—
Research products
—
Antibodies
—
CD and related antigens
—
Anti-Ms CD197 PE
Anti-Ms CD197 PE
Regulatory status
RUO
Antigen
CD197
Clone
4B12
Format
PE
Reactivity
Mouse
Application
FC (QC tested)
Excitation laser
blue (488 nm)
Variant
0.1 mg
1P-735-C100
In stock
180.00 USD
0.025 mg
1P-735-C025
Out of stock
90.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD
0.1 mg
11-261-C100
In stock
90.00 USD
Contact distributor
Product details
Images
References
Isotype
Rat IgG2a kappa
Specificity
The rat monoclonal antibody 4B12 recognizes an extracellular epitope of murine CD197 / CCR7 (chemokine receptor 7), a 43 kDa G-protein-coupled receptor for chemokines CCL19 and CCL21.
Application
FC (QC tested)
Application details
Flow cytometry: Recommended dilution: 1-5 μg/ml.
Reactivity
Mouse
Immunogen
Murine CD197-transfected RBL-2H3 cells
Other names
CCR7, CC-CKR-7, EBI1
Concentration
0.5 mg/ml
Preparation
The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Separation of murine splenocytes stained using anti-mouse CD197 (4B12) PE antibody (concentration in sample 9 μg/ml, red) from unstained murine splenocytes (black) in flow cytometry analysis (surface staining).
Product specific references:
Singh V, Gowthaman U, Jain S, Parihar P, Banskar S, Gupta P, Gupta UD, Agrewala JN: Coadministration of interleukins 7 and 15 with bacille Calmette-Guérin mounts enduring T cell memory response against Mycobacterium tuberculosis. J Infect Dis. 2010 Aug 15;202(3):480-9
PubMed
Adachi K, Osada Y, Nakamura R, Tamada K, Hamano S: Unique T Cells with Unconventional Cytokine Profiles Induced in the Livers of Mice during Schistosoma mansoni Infection. PLoS One. 2013 Dec 16;8(12):e82698.
PubMed
Huggins A, Paschalidis N, Flower RJ, Perretti M, D'Acquisto F: Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation. FASEB J. 2009 Apr;23(4):985-96
PubMed
Eisenbarth SC, Williams A, Colegio OR, Meng H, Strowig T, Rongvaux A, Henao-Mejia J, Thaiss CA, Joly S, Gonzalez DG, Xu L, Zenewicz LA, Haberman AM, Elinav E, Kleinstein SH, Sutterwala FS, Flavell RA: NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells. Nature. 2012 Apr 25;484(7395):510-3
PubMed
Variant
0.1 mg
1P-735-C100
In stock
180.00 USD
0.025 mg
1P-735-C025
Out of stock
90.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD
0.1 mg
11-261-C100
In stock
90.00 USD
Contact distributor
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