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Exbio
—
Research products
—
Antibodies
—
CD and related antigens
—
Anti-Hu TROP2 PerCP-Cy™5.5
Anti-Hu TROP2 PerCP-Cy™5.5
Regulatory status
RUO
Antigen
TROP2
Clone
TrMab-6
Format
PerCP-Cy™5.5
Reactivity
Pig, Human
Application
FC (QC tested)
Excitation laser
blue (488 nm)
Variant
100 tests
T9-898-T100
Ask for delivery term
HERE
330.00 USD
Variant
100 tests
T9-898-T100
Ask for delivery term
HERE
330.00 USD
Contact distributor
Product details
Description
Images
References
SDS download
Isotype
Mouse IgG2b kappa
Specificity
The mouse monoclonal antibody TrMab-6 recognizes an extracellular epitope of TROP2, a type I transmembrane glycoprotein. This antibody is usefull for detection of TROP2 in breast cancer.
Application
FC (QC tested)
Application details
Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 10
6
cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Reactivity
Pig, Human
Negative species
Mouse
Immunogen
TROP2-transfected CHO cells
Preparation
Purified antibody is conjugated with activated tandem dye of activated Peridinin-Chlorophyll Protein-Cyanine 5.5 (PerCP-Cy™5.5) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Licence note
Cy™ and CyDye™ are registered trademarks of Cytiva.
Other names
TACSTD2, EGP1, GP50, M1S1, GA733-1
Antigen description
TROP2 is a cell surface receptor that transduces calcium signals. It belongs to carcinoma-associated antigens. Mutations of TROP2 have been associated with gelatinous drop-like corneal dystrophy.
Entrez Gene ID
4070
UniProt ID
P09758
Separation of MCF-7 cells (red-filled) from leukocytes (black-dashed) in flow cytometry analysis (surface staining) stained using anti-human TROP2 (TrMab-6) PerCP-Cy™5.5 antibody (10 μl reagent per milion cells in 100 μl of cell suspension).
Product specific references:
Sayama Y, Kaneko MK, Kato Y: Development and characterization of TrMab‑6, a novel anti‑TROP2 monoclonal antibody for antigen detection in breast cancer. Mol Med Rep. 2021 Feb;23(2):92.
PubMed
Further SDS language mutations available for download below. Please contact us with request for additional languages on info@exbio.cz
MPAbNaN3_SDS_v1_AU.pdf
MPAbNaN3_SDS_v1_GB.pdf
MPAbNaN3_SDS_v1_TR.pdf
MPAbNaN3_SDS_v6_AT.pdf
MPAbNaN3_SDS_v6_CH.pdf
MPAbNaN3_SDS_v6_CS.pdf
MPAbNaN3_SDS_v6_EN.pdf
MPAbNaN3_SDS_v6_ES.pdf
MPAbNaN3_SDS_v6_FR.pdf
MPAbNaN3_SDS_v6_IT.pdf
MPAbNaN3_SDS_v6_NO.pdf
MPAbNaN3_SDS_v6_PL.pdf
MPAbNaN3_SDS_v6_PT.pdf
MPAbNaN3_SDS_v6_SE.pdf
MPAbNaN3_SDS_v6_SK.pdf
MPAbNaN3_SDS_v6_SL.pdf
MPAbNaN3_SDS_v7_DE.pdf
Variant
100 tests
T9-898-T100
Ask for delivery term
HERE
330.00 USD
Variant
100 tests
T9-898-T100
Ask for delivery term
HERE
330.00 USD
Contact distributor
Datasheet download
Bulk requests
Technical support for this product
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