Exbio — Research products — Antibodies — CD and related antigens — Anti-Hu TROP2 Biotin

Anti-Hu TROP2 Biotin

Anti-Hu TROP2 Biotin
Regulatory status
RUO
Antigen
TROP2
Clone
TrMab-6
Format
Biotin
Reactivity
Pig, Human
Application
IHC, WB, FC (QC tested), ICC
Variant
0.1 mg
1B-898-C100
In stock
180.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD
Contact distributor
Product details
Description
Images
References
Isotype
Mouse IgG2b kappa
Specificity
The mouse monoclonal antibody TrMab-6 recognizes an extracellular epitope of TROP2, a type I transmembrane glycoprotein. This antibody is usefull for detection of TROP2 in breast cancer.
Application
IHC, WB, FC (QC tested), ICC
Application details
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Reactivity
Pig, Human
Negative species
Mouse
Immunogen
TROP2-transfected CHO cells
Concentration
1 mg/ml
Preparation
Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
TACSTD2, EGP1, GP50, M1S1, GA733-1
Antigen description
TROP2 is a cell surface receptor that transduces calcium signals. It belongs to carcinoma-associated antigens. Mutations of TROP2 have been associated with gelatinous drop-like corneal dystrophy.
Entrez Gene ID 4070
UniProt ID P09758
1B-898_FC_Histogram
Separation of MCF-7 cells stained using anti-TROP2 (TrMab-6) Biotin antibody (concentration in sample 1,0 μg/ml, Streptavidin PE, red-filled) from MCF-7 cells unstained by primary antibody (Streptavidin PE, black-dashed) in flow cytometry analysis (surface staining).

Product specific references:

Sayama Y, Kaneko MK, Kato Y: Development and characterization of TrMab‑6, a novel anti‑TROP2 monoclonal antibody for antigen detection in breast cancer. Mol Med Rep. 2021 Feb;23(2):92.
PubMed
Variant
0.1 mg
1B-898-C100
In stock
180.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD
Contact distributor
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