Anti-Hu TROP2 APC

Anti-Hu TROP2 APC
Regulatory status
RUO
Antigen
TROP2
Clone
TrMab-6
Format
APC
Reactivity
Pig, Human
Application
Excitation laser
red (633 nm)
Variant
100 tests
1A-898-T100
In stock
220.00 USD
Variant
0.1 mg
11-261-C100
In stock
220.00 USD
Product details
Description
Images
References
Isotype
Mouse IgG2b kappa
Specificity
The mouse monoclonal antibody TrMab-6 recognizes an extracellular epitope of TROP2, a type I transmembrane glycoprotein. This antibody is usefull for detection of TROP2 in breast cancer.
Application
Application details
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity
Pig, Human
Negative species
Mouse
Immunogen
TROP2-transfected CHO cells
Preparation
Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
TACSTD2, EGP1, GP50, M1S1, GA733-1
Antigen description
TROP2 is a cell surface receptor that transduces calcium signals. It belongs to carcinoma-associated antigens. Mutations of TROP2 have been associated with gelatinous drop-like corneal dystrophy.
Entrez Gene ID 4070
UniProt ID P09758
1A-898_FC_Histogram
Separation of MCF-7 cells (red-filled) from leukocytes (black-dashed) in flow cytometry analysis (surface staining) stained using anti-human TROP2 (TrMab-6) APC antibody (10 μl reagent per milion cells in 100 μl of cell suspension).

Product specific references:

Sayama Y, Kaneko MK, Kato Y: Development and characterization of TrMab‑6, a novel anti‑TROP2 monoclonal antibody for antigen detection in breast cancer. Mol Med Rep. 2021 Feb;23(2):92.
PubMed
Variant
100 tests
1A-898-T100
In stock
220.00 USD
Variant
0.1 mg
11-261-C100
In stock
220.00 USD