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Exbio
—
Research products
—
Antibodies
—
CD and related antigens
—
Anti-Hu TROP2 Alexa Fluor<sup>®</sup> 488
Anti-Hu TROP2 Alexa Fluor
®
488
Regulatory status
RUO
Antigen
TROP2
Clone
TrMab-6
Format
Alexa Fluor
®
488
Reactivity
Pig, Human
Application
IHC, WB, FC (QC tested), ICC
Excitation laser
blue (488 nm)
Variant
100 tests
A4-898-T100
In stock
220.00 USD
Variant
100 tests
A4-898-T100
In stock
220.00 USD
Contact distributor
Product details
Description
Images
References
Isotype
Mouse IgG2b kappa
Specificity
The mouse monoclonal antibody TrMab-6 recognizes an extracellular epitope of TROP2, a type I transmembrane glycoprotein. This antibody is usefull for detection of TROP2 in breast cancer.
Application
IHC, WB, FC (QC tested), ICC
Application details
Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 10
6
cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Reactivity
Pig, Human
Negative species
Mouse
Immunogen
TROP2-transfected CHO cells
Preparation
Purified antibody is conjugated with Alexa Fluor
®
488 NHS ester under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Licence note
Alexa Fluor
®
, Pacific Blue™ and Pacific Orange™ are registered trademarks of Life Technologies Corporation.
Licence label
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com.
Other names
TACSTD2, EGP1, GP50, M1S1, GA733-1
Antigen description
TROP2 is a cell surface receptor that transduces calcium signals. It belongs to carcinoma-associated antigens. Mutations of TROP2 have been associated with gelatinous drop-like corneal dystrophy.
Entrez Gene ID
4070
UniProt ID
P09758
Separation of MCF-7 cells (red-filled) from leukocytes (black-dashed) in flow cytometry analysis (surface staining) stained using anti-human TROP2 (TrMab-6) Alexa Fluor® 488 antibody (4 μl reagent per milion cells in 100 μl of cell suspension).
Product specific references:
Sayama Y, Kaneko MK, Kato Y: Development and characterization of TrMab‑6, a novel anti‑TROP2 monoclonal antibody for antigen detection in breast cancer. Mol Med Rep. 2021 Feb;23(2):92.
PubMed
Variant
100 tests
A4-898-T100
In stock
220.00 USD
Variant
100 tests
A4-898-T100
In stock
220.00 USD
Contact distributor
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SDS download
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