Clinical products
Premium antibodies (GMP)
Intracellular staining
Surface staining
Hematology
Kits
Lysing solutions
Premixed antibody combinations
Single color antibodies
Immunodeficiency
Kits
Lysing solutions
Mitogens
Premixed antibody combinations
Single color antibodies
Reproductive immunology
Kits
Lysing solutions
Premixed antibody combinations
New products
Allergy
Kits
Recombinant allergens
Allergen extracts
Other allergens
Research products
Antibodies
CD and related antigens
Blood group antigens
Premixed antibody combinations
Serum, plasma, and secreted proteins
Cytoskeleton and ECM
Isotype controls
MHC antigens
Nucleus
Other intracellular antigens
Small organic molecules
Tags and labels
Microbiology and virology
Accessory reagents
Annexin binding
DNA-binding probes
Lineage cocktail
Lysing solutions
Recombinant proteins
Recombinant allergens
Animal
Food
House Dust Mite
Mold
Pollen
Venom
Kits
New products
Dry Reagents
About exbio
Company
OEM and Commercial Supplies
Blog
Events and Conferences
Promotions
Inquiries
Technical resources
International distributors
Contact
Jobs
E-mail
*
Password
*
Remember me
Forgotten password
Log in
Register
E-mail
Send request
Log in
Exbio
—
Research products
—
Antibodies
—
CD and related antigens
—
Anti-Hu HER3 Purified
Anti-Hu HER3 Purified
Regulatory status
RUO
Antigen
HER3
Clone
H3Mab-17
Format
Purified
Reactivity
Human
Application
FC (QC tested)
Variant
0.1 mg
11-901-C100
In stock
140.00 USD
Variant
0.1 mg
11-901-C100
In stock
140.00 USD
Contact distributor
Product details
Description
Images
Isotype
Mouse IgG2a kappa
Specificity
The mouse monoclonal antibody H3Mab-17 recognizes an extracellular epitope on human HER3, a member of EGFR family of receptor tyrosine kinases, which is overexpressed in many cancers.
Application
FC (QC tested)
Application details
Flow cytometry: Recommended dilution: 1-5 μg/ml.
Reactivity
Human
Immunogen
HER3-transfected CHO cells
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
ERBB3, FERLK, LCCS2
Antigen description
HER3 (ERBB3) is a transmembrane protein of the epidermal growth factor receptor family, although it does not have an active tyrosine kinase domain. It can bind its ligand, but for further signaling it needs heterodimerization with other receptor tyrosine kinases of EGFR family. Overexpression of HER3 has been observed in many carcinomas. Activity of HER3 can be modulated by one of its isoforms, that is secreted from the cell, as its lacks the transmembrane domain.
Entrez Gene ID
2065
UniProt ID
P21860
Separation of MCF-7 cells stained using anti-HER3 (H3Mab-17) purified antibody (concentration in sample 0,6 μg/ml, GAM APC, red-filled) from MCF-7 cells unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).
Variant
0.1 mg
11-901-C100
In stock
140.00 USD
Variant
0.1 mg
11-901-C100
In stock
140.00 USD
Contact distributor
Datasheet download
SDS download
CS
EN
Bulk requests
Technical support for this product
Related products
ED7066
EXCELLYSE Easy
-134%
Clone
Reg. status
CE IVD
Application
FC
100 ml
200.00 USD
ED7065
EXCELLYSE I
-134%
Clone
Reg. status
CE IVD
Application
FC
100 ml
60.00 USD
ED7068
EXCELLYSE Live
-134%
Clone
Reg. status
RUO
Application
FC
100 ml
50.00 USD
11-724-C100
Mouse IgG2a Isotype Control Purified
-134%
Clone
MOPC-173
Reg. status
RUO
Application
ELISA, FC, FC(IC), IP, WB, IHC(F), IHC(P), ICC
0.1 mg
105.00 USD
11-458-C100
Mouse IgG2a Isotype Control Purified
-134%
Clone
PPV-04
Reg. status
RUO
Application
ELISA, FC, FC(IC), IP, WB, IHC(F), IHC(P), ICC
0.1 mg
105.00 USD
Continue to checkout
×
Zavřít