Exbio — Research products — Antibodies — CD and related antigens — Anti-Hu CD93 FITC

Anti-Hu CD93 FITC

Regulatory status

RUO

Antigen

CD93

Clone

VIMD2

Format

FITC

Reactivity

Human

Application

FC (QC tested)

Excitation laser

blue (488 nm)

Variant

100 tests

1F-794-T100

In stock

180.00 USD

Variant

0.1 mg

11-261-C100

In stock

180.00 USD

Contact distributor

Product details

Description

Images

References

Isotype

Mouse IgG1

Specificity

The mouse monoclonal antibody VIMD2 recognizes an extracellular epitope on CD93, an approximately 110-120 kDa glycoprotein expressed mainly on myeloid cells and endothelial cells.

Workshop

HLDA I: WS Code M 3; HLDA V: WS Code M17, BP231; HLDA VI: WS Code MR8

Application

FC (QC tested)

Application details

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Reactivity

Human

Immunogen

KG1 cell line

Preparation

Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Formulation

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Other names

C1QR1, C1qRP, ECSM3, MXRA4, C1qR(P), dJ737E23.1

Antigen description

CD93 (also known as C1qR1) is a type I transmembrane glycoprotein containing extracellular N-terminal C-type lectin domain and five EGF-like domains, and an intracellular tail interacting with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. CD93 was reported to serve as a receptor for complement component C1q, but this function has not been fully elucidated yet. CD93 is involved in intercellular adhesion and in the clearance of apoptotic cells.

Entrez Gene ID 22918

UniProt ID Q9NPY3

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD93 (VIMD2) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).

Separation of human monocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD93 (VIMD2) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).

Product specific references:

Steinberger P, Szekeres A, Wille S, Stöckl J, Selenko N, Prager E, Staffler G, Madic O, Stockinger H, Knapp W: Identification of human CD93 as the phagocytic C1q receptor (C1qRp) by expression cloning. J Leukoc Biol. 2002 Jan;71(1):133-40.
PubMed

Variant

100 tests

1F-794-T100

In stock

180.00 USD

Variant

0.1 mg

11-261-C100

In stock

180.00 USD

Contact distributor

Datasheet download