Anti-Hu CD85h Purified

Anti-Hu CD85h Purified
Regulatory status
RUO
Antigen
CD85h
Clone
24
Format
Purified
Reactivity
Non-human primates, Human
Variant
0.1 mg
11-925-C100
In stock
140.00 USD
Variant
0.1 mg
11-261-C100
In stock
140.00 USD
Product details
Description
Images
References
Isotype
Mouse IgG2b kappa
Specificity
The mouse monoclonal antibody 24 recognizes an extracellular epitope of CD85h, an approximately 70 kDa transmembrane glycoprotein.
Application details
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Reactivity
Non-human primates, Human
Immunogen
human CD85h transfectants
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
ILT1, LIR7, LILRA2
Antigen description
CD85h (leukocyte Ig-like receptor A2) is a type I transmembrane glycoprotein, associating with Fc receptor gamma chain, to serve as an activating immunoreceptor. In the result, however, CD85h signaling leads to suppression of dendritic cell differentiation and antigen presentation, and of innate immune responses. This glycoprotein is expressed mainly on monocytes, macrophages, and myeloid dendritic cells, at a lower level on granulocyte and NK cell subsets.
Entrez Gene ID 11027
UniProt ID Q8N149
11-925_FC_Profil značení
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD85h (24) purified antibody (concentration in sample 0,56 μg/ml, GAM APC).
11-925_FC_Histogram
Separation of human monocytes (red-filled) from human lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human CD85h (24) purified antibody (concentration in sample 0,56 μg/ml, GAM APC).

Product specific references:

Lee DJ, Sieling PA, Ochoa MT, Krutzik SR, Guo B, Hernandez M, Rea TH, Cheng G, Colonna M, Modlin RL: LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells. J Immunol. 2007 Dec 15;179(12):8128-36.
PubMed
Variant
0.1 mg
11-925-C100
In stock
140.00 USD
Variant
0.1 mg
11-261-C100
In stock
140.00 USD

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