Anti-Hu CD75 Purified

Anti-Hu CD75 Purified
Regulatory status
RUO
Antigen
CD75
Clone
LN1
Format
Purified
Reactivity
Human
Variant
0.1 mg
11-922-C100
In stock
140.00 USD
Variant
0.1 mg
11-261-C100
In stock
140.00 USD
Product details
Description
Images
References
Isotype
Mouse IgM kappa
Specificity
The mouse monoclonal antibody LN1 recognizes CD75, a lactosamine structure present mainly on the surface of B cell types.
Application details
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Reactivity
Human
Immunogen
Stimulated human PBL
Concentration
1 mg/ml
Preparation
Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
Formulation
Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
lactosamine
Antigen description
CD75 is a lactosamine structure, which is present mainly on the surface of germinal center B cells. With lower level it is present on other mature B cells, and it is downregulated during differentiation to plasma cells. It is a marker which differentiates between malignant B cell types.
11-922_FC_Profil značení.tif
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD75 (LN1) purified antibody (concentration in sample 5 μg/ml, GAM APC).
11-922_FC_Histogram
Separation of human CD75 positive lymphocytes (red-filled) from CD75 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD75 (LN1) purified antibody (concentration in sample 5 μg/ml, GAM APC).

Product specific references:

Fromm JR, Thomas A, Wood BL: Characterization and purification of neoplastic cells of nodular lymphocyte predominant hodgkin lymphoma from lymph nodes by flow cytometry and flow cytometric cell sorting. Am J Pathol. 2017 Feb;187(2):304-317.
PubMed
Epstein AL, Marder RJ, Winter JN, Fox RI: Two new monoclonal antibodies (LN-1, LN-2) reactive in B5 formalin-fixed, paraffin-embedded tissues with follicular center and mantle zone human B lymphocytes and derived tumors. J Immunol. 1984 Aug;133(2):1028-36.
PubMed
Virtanen S, Schulte R, Stingl J, Caldas C, Shehata M: High-throughput surface marker screen on primary human breast tissues reveals further cellular heterogeneity. Breast Cancer Res. 2021 Jun 13;23(1):66.
PubMed
Variant
0.1 mg
11-922-C100
In stock
140.00 USD
Variant
0.1 mg
11-261-C100
In stock
140.00 USD

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