Exbio — Research products — Antibodies — CD and related antigens — Anti-Hu CD7 Purified

Anti-Hu CD7 Purified

Anti-Hu CD7 Purified
Regulatory status
RUO
Antigen
CD7
Clone
MEM-186
Format
Purified
Reactivity
Human
Application
IP, WB, FC (QC tested), IHC(P)
Variant
0.1 mg
11-206-C100
In stock
130.00 USD
0.025 mg
11-206-C025
Out of stock
65.00 USD
Variant
0.1 mg
11-261-C100
In stock
130.00 USD
0.1 mg
11-261-C100
In stock
65.00 USD
Contact distributor
Product details
References
Isotype
Mouse IgG1
Specificity
The antibody MEM-186 reacts with an extracellular epitope of CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
Workshop
HLDA VI: WS Code T 6T-015
Application
IP, WB, FC (QC tested), IHC(P)
Application details
Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/ml; positive tissue: spleen.
Flow cytometry: Recommended dilution: 2 μg/ml.
Western blotting: Non-reducing conditions.
Reactivity
Human
Immunogen
Human acute myelogenous leukaemia cell line KG-1.
Other names
GP40, TLA, TP41, LEU-9
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

General references:

Nishimura M, Takanashi M, Okazaki H, Satake M, Nakajima K: Role of CD7 expressed in lung microvascular endothelial cells as Fc receptor for immunoglobulin M. Endothelium. 2006 Jul-Aug;13(4):287-92.
PubMed
Chang H, Yeung J, Brandwein J, Yi QL: CD7 expression predicts poor disease free survival and post-remission survival in patients with acute myeloid leukemia and normal karyotype. Leuk Res. 2007 Feb;31(2):157-62. Epub 2006 Jul 11.
PubMed
Lam GK, Liao HX, Xue Y, Alam SM, Scearce RM, Kaufman RE, Sempowski GD, Haynes BF. Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-gamma. J Clin Immunol. 2005 Jan;25(1):41-9.
PubMed
Alaibac M, Pigozzi B, Belloni-Fortina A, Michelotto A, Saponeri A, Peserico A. CD7 expression in reactive and malignant human skin T-lymphocytes. Anticancer Res. 2003 May-Jun;23(3B):2707-10.
PubMed
Variant
0.1 mg
11-206-C100
In stock
130.00 USD
0.025 mg
11-206-C025
Out of stock
65.00 USD
Variant
0.1 mg
11-261-C100
In stock
130.00 USD
0.1 mg
11-261-C100
In stock
65.00 USD
Contact distributor
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Bulk requests
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