Anti-Hu CD37 Purified

Anti-Hu CD37 Purified
Regulatory status
RUO
Antigen
CD37
Clone
MB-1
Format
Purified
Reactivity
Human
Variant
0.1 mg
11-923-C100
In stock
140.00 USD
Variant
0.1 mg
11-261-C100
In stock
140.00 USD
Product details
Description
Images
References
Isotype
Mouse IgG1 kappa
Specificity
The mouse monoclonal antibody MB-1 recognizes an extracellular epitope of CD37, a tetraspanin family transmembrane glycoprotein.
Application details
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Reactivity
Human
Immunogen
lymphomatous lymph node cells
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
GP52-40, tetraspanin 26
Antigen description
CD37 is a 40-64 kDa tetraspanin family glycoprotein, which forms complexes in the B cell membrane with MHC class II, CD53, CD81, and CD82. It is expressed highly on mature B cells and neoplastic B cells, but it is lost on plasma cells, as well as on pro-B cells. Lower expression was detected on monocytes, macrophages, and dendritic cells.
Entrez Gene ID 951
UniProt ID P11049
11-923_FC_Profil značení
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD37 (MB-1) purified antibody (concentration in sample 0,2 μg/ml, GAM APC).
11-923_FC_Dot-plot
Flow cytometry multicolor surface staining of human lymphocytes stained using anti-human CD37 (MB-1) purified antibody (concentration in sample 0,2 μg/ml, GAM APC) and anti-human CD19 (LT19) PE antibody (20 μl reagent / 100 μl of peripheral whole blood).
11-923_FC_Histogram
Separation of human CD37 positive lymphocytes (red-filled) from human CD37 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human CD37 (MB-1) purified antibody (concentration in sample 0,2 μg/ml, GAM APC).

Product specific references:

Link MP, Bindl J, Meeker TC, Carswell C, Doss CA, Warnke RA, Levy R: A unique antigen on mature B cells defined by a monoclonal antibody. J Immunol. 1986 Nov 1;137(9):3013-8.
PubMed
Press OW, Eary JF, Badger CC, Martin PJ, Appelbaum FR, Levy R, Miller R, Brown S, Nelp WB, Krohn KA: Treatment of refractory non-Hodgkin's lymphoma with radiolabeled MB-1 (anti-CD37) antibody. J Clin Oncol. 1989 Aug;7(8):1027-38.
PubMed
Variant
0.1 mg
11-923-C100
In stock
140.00 USD
Variant
0.1 mg
11-261-C100
In stock
140.00 USD

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