Anti-Hu CD344 Purified

Anti-Hu CD344 Purified
Regulatory status
RUO
Antigen
CD344
Clone
CH3A4A7
Format
Purified
Reactivity
Human, Non-human primates
Application
Variant
0.1 mg
11-834-C100
In stock
140.00 USD
Variant
0.1 mg
11-261-C100
In stock
140.00 USD
Product details
Description
Images
References
Isotype
Mouse IgG1 kappa
Specificity
The mouse monoclonal antibody CH3A4A7 recognizes an extracellular epitope of CD344 (Frizzled 4), a 7-TM protein of G-protein-coupled receptor family, which is a marker for neuronal stem cells.
Workshop
HLDA Workshop 2006
Application
Application details
Flow cytometry: Recommended dilution: 1-4 µg/ml
Reactivity
Human, Non-human primates
Immunogen
WERI-RB-1 retinoblastoma cells
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
Frizzled-4, FZD4, EVR1, FEVR, GPCR
Antigen description
CD344 (Frizzled class receptor 4) is a G-protein coupled 7-TM protein, predominantly expressed in fetal neuronal progenitor cells, neuronal intestinal cells, as well as in the kidney, lung, brain, and liver. CD344 is important for regulation of cell polarity, proliferation, and tissue development. Defects in CD344 expression, or its mutation, lead e.g. to serious failures in retinal vascularization, defects in cerebellum, progressive hearing loss, or impaired corpora lutea formation and function.
Entrez Gene ID 8322
UniProt ID Q9ULV1
11-834_FC_Histogram
Separation of HeLa cells (red-filled) from human peripheral whole blood cells (black-dashed) in flow cytometry analysis (surface staining) stained using anti-human CD344 (CH3A4A7) purified antibody (concentration in sample 1,7 μg/ml, GAM APC).

Product specific references:

Nothelfer K, Obermayr F, Belz N, Reinartz E, Bareiss PM, Bühring HJ, Beschorner R, Just L: Expression of the Wnt Receptor Frizzled-4 in the Human Enteric Nervous System of Infants. Stem Cells Int. 2016;2016:9076823.
PubMed
Variant
0.1 mg
11-834-C100
In stock
140.00 USD
Variant
0.1 mg
11-261-C100
In stock
140.00 USD

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