Anti-Hu CD328 Purified

Anti-Hu CD328 Purified
Regulatory status
RUO
Antigen
CD328
Clone
6-434
Format
Purified
Reactivity
Human
Application
Variant
0.1 mg
11-799-C100
In stock
143.00 USD

0.025 mg
11-799-C025
Delivery 1 week
71.50 USD
Variant
0.1 mg
11-799-C100
In stock
143.00 USD

0.025 mg
11-799-C025
Delivery 1 week
71.50 USD
Product details
Description
Images
References
SDS download
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody 6-434 recognizes an extracellular epitope of CD328 (Siglec-7), a 75 kDa transmembrane glycoprotein expressed mainly on NK cells, dendritic cells and monocytes.
Workshop
HLDA VIII: WS Code ARN-80652
Application
Application details
Flow cytometry: Recommended dilution: 1-4 µg/ml
Reactivity
Human
Immunogen
human dendritic cells
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
SIGLEC7, p75/AIRM1, D-siglec
Antigen description
CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells.
Entrez Gene ID 27036
UniProt ID Q9Y286
11-799_FC_Profil Značení
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD328 (6-434) purified antibody (concentration in sample 3 μg/ml, GAM APC).
11-799_FC_Histogram
Separation of human CD328 positive lymphocytes (red-filled) from CD328 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD328 (6-434) purified antibody (concentration in sample 3 μg/ml, GAM APC).

Product specific references:

Bradley T, Peppa D, Pedroza-Pacheco I, Li D, Cain DW, Henao R, Venkat V, Hora B, Chen Y, Vandergrift NA, Overman RG, Edwards RW, Woods CW, Tomaras GD, Ferrari G, Ginsburg GS, Connors M, Cohen MS, Moody MA, Borrow P, Haynes BF: RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses. Cell. 2018 Oct 4;175(2):387-399
PubMed
Variant
0.1 mg
11-799-C100
In stock
143.00 USD

0.025 mg
11-799-C025
Delivery 1 week
71.50 USD
Variant
0.1 mg
11-799-C100
In stock
143.00 USD

0.025 mg
11-799-C025
Delivery 1 week
71.50 USD

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