Anti-Hu CD326 Purified

Anti-Hu CD326 Purified
Regulatory status
RUO
Antigen
CD326
Clone
323/A3
Format
Purified
Reactivity
Human
Application
FC, IP, WB, IHC(P), ICC
Variant
0.1 mg
11-582-C100
In stock

0.025 mg
11-582-C025
In stock
Variant
0.1 mg
11-261-C100
In stock

0.1 mg
11-261-C100
In stock
Product details
Images
References
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody 323/A3 recognizes an extracellular epitope of CD326 / EpCAM, a marker of epithelial lineages, that is over-expressed in many carcinomas.
Application
FC, IP, WB, IHC(P), ICC
Reactivity
Human
Negative species
Rat
Immunogen
Human breast cancer MCF-7 cells
Other names
EPCAM, Ep-CAM, GA733-2, EGP314, KSA, KS 1/4 antigen, Trop-1, M4S1, DIAR5, MIC18, TROP1
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Exbio licence note
Unless indicated otherwise, all products are For Research Use Only and not for diagnostic use. In vivo diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s. © 2019 EXBIO Praha, a.s. All rights reserved.
11-582 WB
Western blotting analysis (non-reducing conditions) of whole cell lysate of MCF-7 human breast adenocarcinoma cell line using anti-CD326 / EpCAM (323/A3).
11-582 WB2
Western blotting analysis (non-reducing conditions) of whole cell lysate of MCF-7 human breast adenocarcinoma cell line using anti-CD326 / EpCAM (323/A3).

Product specific references:

Kirman I, Jenkins D, Fowler R, Whelan RL: Naturally occurring antibodies to epithelial cell adhesion molecule (EpCAM). Dig Dis Sci. 2003 Dec;48(12):2306-9.
PubMed
Winter MJ, Nagtegaal ID, van Krieken JH, Litvínov SV: The epithelial cell adhesion molecule (Ep-CAM) as a morphoregulatory molecule is a tool in surgical pathology. Am J Pathol. 2003 Dec;163(6):2139-48.
PubMed
Balzar M, Briaire-de Bruijn IH, Rees-Bakker HA, Prins FA, Helfrich W, de Leij L, Riethmüller G, Alberti S, Warnaar SO, Fleuren GJ, Litvínov SV: Epidermal growth factor-like repeats mediate lateral and reciprocal interactions of Ep-CAM molecules in homophilic adhesions. Mol Cell Biol. 2001 Apr;21(7):2570-80.
PubMed
Balzar M, Bakker HA, Briaire-de-Bruijn IH, Fleuren GJ, Warnaar SO, Litvinov SV: Cytoplasmic tail regulates the intercellular adhesion function of the epithelial cell adhesion molecule. Mol Cell Biol. 1998 Aug;18(8):4833-43.
PubMed
Litvínov SV, Bakker HA, Gourevitch MM, Velders MP, Warnaar SO: Evidence for a role of the epithelial glycoprotein 40 (Ep-CAM) in epithelial cell-cell adhesion. Cell Adhes Commun. 1994 Oct;2(5):417-28.
PubMed
Litvínov SV, Velders MP, Bakker HA, Fleuren GJ, Warnaar SO: Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule. J Cell Biol. 1994 Apr;125(2):437-46.
PubMed
Edwards DP, Grzyb KT, Dressler LG, Mansel RE, Zava DT, Sledge GW Jr, McGuire WL: Monoclonal antibody identification and characterization of a Mr 43,000 membrane glycoprotein associated with human breast cancer. Cancer Res. 1986 Mar;46(3):1306-17.
PubMed
Variant
0.1 mg
11-582-C100
In stock

0.025 mg
11-582-C025
In stock
Variant
0.1 mg
11-261-C100
In stock

0.1 mg
11-261-C100
In stock