Anti-Hu CD316 Purified

Anti-Hu CD316 Purified
Regulatory status
RUO
Antigen
CD316
Clone
8A12
Format
Purified
Reactivity
Human
Variant
0.1 mg
11-940-C100
In stock
154.00 USD
Variant
0.1 mg
11-940-C100
In stock
154.00 USD
Product details
Description
Images
References
SDS download
Isotype
Mouse IgG2a
Specificity
The mouse monoclonal antibody 8A12 recognizes an extracellular epitope of CD316, a type I transmembrane glycoprotein, expressed mainly by lymphocytes, NK cells and in a broad range of tissues.
Workshop
HCDM listed
Application details
Flow cytometry: Recommended dilution: 1-5 µg/ml
Reactivity
Human
Immunogen
human leukocytes
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
EWI2, PGRL, KCT-4, LIR-D1, IGSF8
Antigen description
CD316 is an approximately 63 kDa transmembrane glycoprotein, which forms stable complexes with CD9, as well as with CD81. It seems that CD316 participates in regulation of cell polarity and motility, in cell proliferation, oocyte fertilization and tumor cell metastasis. It is expressed mainly by lymphocytes, NK cells and in a broad range of tissues, and associates with actin cytoskeleton.
Entrez Gene ID 93185
UniProt ID Q969P0
11-940_FC_Profil Značení
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD316 (8A12) purified antibody (concentration in sample 5 μg/ml, GAM APC).
11-940_FC_Histogram
Separation of human lymphocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD316 (8A12) purified antibody (concentration in sample 5 μg/ml, GAM APC).

Product specific references:

Gordón-Alonso M, Sala-Valdés M, Rocha-Perugini V, Pérez-Hernández D, López-Martín S, Ursa A, Alvarez S, Kolesnikova TV, Vázquez J, Sánchez-Madrid F, Yáñez-Mó M: EWI-2 association with α-actinin regulates T cell immune synapses and HIV viral infection. J Immunol. 2012 Jul 15;189(2):689-700.
PubMed
Variant
0.1 mg
11-940-C100
In stock
154.00 USD
Variant
0.1 mg
11-940-C100
In stock
154.00 USD

Related products

-134%
Reg. statusCE IVD
ApplicationFC
100 ml
220.00 USD
-134%
Reg. statusCE IVD
ApplicationFC
100 ml
66.00 USD
-134%
Reg. statusRUO
ApplicationFC
100 ml
55.00 USD
-134%
CloneMOPC-173
Reg. statusRUO
0.1 mg
115.50 USD